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Diphenyleneiodonium chloride
Cat. No.:
0225LY-1256
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by NMR, and LC-MS.
Size:
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Product Overview
Description:
Diphenyleneiodonium chloride is an irreversible inhibitor of eNOS and iNOS (with IC50 values of 0.3 μM and 50 nM, respectively) and demonstrates a broad range of bactericidal effects.
Synonym:
DPI; 4673-26-1; Diphenyleneiodonium chloride; 4673-26-1; Dibenziodolium chloride; DPI; 2,2'-biphenylyleneiodonium chloride; dibenzo(b,d)iodolium chloride; 8-iodoniatricyclo[7.4.0.02,7]trideca-1(13),2,4,6,9,11-hexaene;chloride; Dibenziodolium, chloride; DPI chloride; dibenzo[b,d]iodol-5-ium chloride
CAS No.:
4673-26-1
Compound CID:
2733504
Formula:
C12H8ClI
Formula Weight:
314.55
Specification
Targets&IC50:
eNOS: 0.3 µM; iNOS: 50 nM
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Diphenyleneiodonium chloride can be used in redox biology to investigate the inhibition of NADPH oxidase and other flavoprotein enzymes.
Library Information
Target:
TRP/TRPV channel; NADPH; NOS
Receptor:
NADPH oxidase; NOS; TRP channel
Pathways:
Membrane transporter/Ion channel; NF-κB; Immunology/Inflammation; Metabolism
Plate Number:
AOCL-17
Plate Location:
b3
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
6 mg/mL; 19.07 mM
