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Diosmetin
Cat. No.:
OB0225WX-2063
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
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Product Overview
Description:
Diosmetin is a natural flavonoid derivative that has been identified to function as a weak agonist of the TrkB receptor.
Synonym:
Luteolin 4-methyl ether; 520-34-3; 5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-chromen-4-one; Luteolin 4'-methyl ether; 4'-Methylluteolin; Salinigricoflavonol; Diosmetine; Pillon; 3',5,7-trihydroxy-4'-methoxyflavone; 5,7,3'-Trihydroxy-4'-methoxyflavone; 5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chromen-4-one; MFCD00017425; 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-; 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-benzopyrone; 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one; Flavone, 3',5,7-trihydroxy-4'-methoxy-; Luteolin 4-methyl ether; SR-05000002196; 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one (Diosmetin); 3',5,7-trihydroxy-4'-methoxy flavone; 2-(4-methoxy-3-oxidanyl-phenyl)-5,7-bis(oxidanyl)chromen-4-one; 5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-1-benzopyran-4-one; J8D
CAS No.:
520-34-3
Compound CID:
5281612
Formula:
C16H12O6
Formula Weight:
300.26
Specification
Targets&IC50:
CYP1A enzyme(human; HepG2 cells): 40 μM
Relative Density:
1.517 g/cm3 at 20°C.
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Diosmetin is utilized in phytochemical research as a bioactive flavonoid to study its anti-inflammatory and antioxidant activities, as well as its ability to inhibit specific metabolic enzymes.
Library Information
Target:
P450; Trk receptor
Receptor:
CYP1A1; Cytochrome P450; TrkB
Pathways:
Tyrosine kinase/adaptors; Metabolism
Plate Number:
AOCL-27
Plate Location:
d6
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
18.33 mg/mL; 61.06 mM
Water Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
Ethanol Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
ALogP:
2.394
HBA_Count:
3
HBD_Count:
3
Rotatable Bond:
2





