Deferasirox (ICL-670)

Cat. No.: OB0225WX-2439

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and HPLC.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: Deferasirox (ICL-670) is a tridentate iron chelator that also functions as an inducer of CYP3A4 and an inhibitor of the CYP2C8 and CYP1A2 metabolic enzymes.

Synonym: CGP-72670, ICL-670; 201530-41-8; Deferasirox; Exjade; ICL 670; ICL670A; ICL-670A; ICL670; Deferasiroxum; ICL-670; Jadenu; ICL 670A; Osveral; Jadenu Sprinkle; 4-[3,5-Bis(2-hydroxyphenyl)-1,2,4-triazol-1-yl]benzoic acid; 4-[3,5-bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic acid; 4-(3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl)benzoic acid; Benzoic acid, 4-[3,5-bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]-; Benzoic acid, 4-(3,5-bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl)-; NCGC00181754-01; 4-[bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic acid; 4-{3,5-bis[(1E)-6-oxocyclohexa-2,4-dien-1-ylidene]-1,2,4-triazolidin-1-yl}benzoic acid; 4-(3,5-Bis(6-oxocyclohexa-2,4-dien-1-ylidene)-1,2,4-triazolidin-1-yl)benzoic acid; 4-[3,5-bis(6-oxocyclohexa-2,4-dien-1-ylidene)-1,2,4-triazolidin-1-yl]benzoic acid; 4-[(3Z,5E)-3,5-bis(6-oxocyclohexa-2,4-dien-1-ylidene)-1,2,4-triazolidin-1-yl]benzoic acid

CAS No.: 201530-41-8

Compound CID: 214348

Formula: C₂₁H₁₅N₃O₄

Formula Weight: 373.36

Specification

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Deferasirox (ICL-670) is utilized in hematology and clinical pharmacology research as an orally active iron chelator to investigate the removal of excess systemic iron in models of chronic iron overload.