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Columbin
Cat. No.:
0225LY-0706
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
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Product Overview
Description:
Columbin serves as a chemopreventive agent against human colon cancer and displays anti-inflammatory properties, specifically inhibiting PLA2-mediated hydrolysis of red blood cell ghosts in a dose-dependent fashion.
Synonym:
546-97-4; (1S,2S,3S,5S,8R,11R,12S)-5-(Furan-3-yl)-12-hydroxy-3,11-dimethyl-6,14-dioxatetracyclo[10.2.2.02,11.03,8]hexadec-15-ene-7,13-dione; 4-Hydroxy-15,16-epoxycleroda-2,13(16),14-trieno-17,12-18,1-biscarbolactone; 1,4-Etheno-3H,7H-benzo(1,2-c:3,4-c')dipyran-3,7-dione, 9-(3-furanyl)-1,4,4a,5,6,6a,9,10,10a,10b-decahydro-4-hydroxy-4a,10a-dimethyl-, (1R-(1alpha,4beta,4aalpha,6abeta,9beta,10abeta,10balpha))-
CAS No.:
546-97-4
Compound CID:
188289
Formula:
C20H22O6
Formula Weight:
358.39
Specification
Targets&IC50:
COX-2: 53.1 μM (EC50); COX-1: 327 μM (EC50)
Relative Density:
1.36 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Columbin can be used in biochemical studies to explore its role in modulating inflammatory pathways and its potential as an anti-tumor agent.
Library Information
Target:
Parasite protein; COX; Phospholipase
Receptor:
COX; Parasite protein; PLA2
Pathways:
Microbiology/Virology; Neuronal signaling; Immunology/Inflammation; Metabolism
Plate Number:
AOCL-10
Plate Location:
b3
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
55 mg/mL; 153.46 mM
