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Cinchonidine
Cat. No.:
0225LY-0695
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and LC-MS.
Size:
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Product Overview
Description:
Cinchonidine is an alkaloid derived from Cinchona officinalis that serves as both a stereoisomer and a pseudo-enantiomer of cinchonine.
Synonym:
α-Quinidine; L-Cinchonidine; 485-71-2; (-)-Cinchonidine; Cinchovatine; (8S,9R)-Cinchonidine; (8-alpha,9R)-Cinchonan-9-ol; (8S,9R)-cinchonan-9-ol; (R)-quinolin-4-yl((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methanol; (R)-[(1R,2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](quinolin-4-yl)methanol; (S)-[(2R,4R,5S)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-quinolin-4-ylmethanol
CAS No.:
485-71-2
Compound CID:
101744
Formula:
C19H22N2
Formula Weight:
294.39
Specification
Targets&IC50:
SERT I172M (human): 36 μM (Ki); SERT S438T (human): 196 μM (Ki); dSERT: 330 μM (Ki); SERT Y95F (human): 15 μM (Ki); sEH: 4.2 μM (Ki)
Relative Density:
1.0863 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Cinchonidine can be used in stereochemistry and pharmacology to investigate its role as an antimalarial and a chiral resolving agent.
Library Information
Target:
5-HT receptor; Serotonin transporter
Receptor:
5-HT receptor; SERT
Pathways:
Microbiology/Virology; GPCR/G protein signaling; Neuronal signaling
Plate Number:
AOCL-10
Plate Location:
a2
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
8.57 mg/mL; 29.11 mM
Water Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
Ethanol Max Solubility:
55 mg/mL; 186.83 mM
