APD597

Cat. No.: OB0225WX-2268

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR.

Size:

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Product Overview

Description: APD597 is an orally active small molecule that functions at the molecular level as an agonist of the GPR119 receptor.

Synonym: JNJ-38431055; 897732-93-3; ADP-597; Isopropyl 4-((5-methoxy-6-((2-methyl-6-(methylsulfonyl)pyridin-3-yl)amino)pyrimidin-4-yl)oxy)piperidine-1-carboxylate; APD597 (JNJ-38431055); APD 597; JNJ 38431055; Propan-2-yl 4-[5-methoxy-6-[(2-methyl-6-methylsulfonylpyridin-3-yl)amino]pyrimidin-4-yl]oxypiperidine-1-carboxylate; APD-597; APD597(JNJ-38431055); 4-[6-(6-methanesulfonyl-2-methyl-pyridin-3-ylamino)-5-methoxy-pyrimidin-4-yloxy]-piperidine-1-carboxylic acid isopropyl ester; Isopropyl 4-(5-methoxy-6-(2-methyl-6-(methylsulfonyl)pyridin-3-ylamino)pyrimidin-4-yloxy)piperidine-1-carboxylate; Propan-2-yl 4-({6-[(6-methanesulfonyl-2-methylpyridin-3-yl)amino]-5-methoxypyrimidin-4-yl}oxy)piperidine-1-carboxylate

CAS No.: 897732-93-3

Compound CID: 11691484

Formula: C₂₁H₂₉N₅O₆S

Formula Weight: 479.55

Specification

Targets&IC50: GPR119 (human): 46 nM

Relative Density: 1.311 g/cm³

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: APD597 is employed in metabolic disease research as a selective GPR119 agonist to study the regulation of glucose homeostasis through the dual stimulation of insulin and GLP-1 secretion.