AdipoUpX™ Human TFAP2B MSCV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human TFAP2B MSCV Particle (Overexpression) is engineered to support efficient and stable expression of the human TFAP2B transcription factor. TFAP2B regulates adipocyte differentiation, lipid metabolism, and energy balance, with genetic associations reported in obesity susceptibility. This MSCV-based vector supports robust expression across stem cells and diverse mammalian cell systems. Flexible reporter gene options are available, and all viral preparations are released only after comprehensive QC validation.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Final QC confirmed the correct molecular size and integrity of the insert through specific PCR amplification.

Sterility Test: No microbial contamination was detected in any product.

Mycoplasma Test: No mycoplasma presence was detected in this final viral preparation upon comprehensive testing.

Other QC: Our service scope includes both customized supplementary testing and comprehensive in vitro/in vivo transduction assessments.

Storage: The necessity of immediate transfer to -80 °C storage following receipt is crucial for upholding the product's integrity.

Stability: Biological activity remains intact for 6-12 months when stored at -80°C. Once removed from the freezer, the diluted working material is stable for up to 2-3 weeks at 4°C.

Shipping Condition: Our MSCV retroviral products are shipped using dry ice.

Handling Notes: Store the vector according to specified conditions and aliquot it immediately upon receipt into low-protein-binding tubes, which is necessary to maintain titer because viral particles are highly sensitive to both temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Throughout all operational processes, users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements. Although our company commits to product quality via rigorous internal QC inspections, the complexity of experimental conditions means we cannot guarantee product performance or experimental results in any specific application.

Target Profile

Gene Name: TFAP2B

Full Name: Transcription factor AP-2 beta

Gene Symbol: PDA2; AP-2B; AP2-B; AP-2beta

Gene ID: 7021

RefSeq ID-1: NP_003212.2

RefSeq ID-2: NM_003221.4

Summary: TFAP2B encodes an AP-2 family transcription factor that regulates gene expression through sequence-specific DNA binding and dimerization. During development, it controls cell proliferation and lineage commitment. Genetic and functional studies indicate that TFAP2B also influences adipose tissue biology and body weight regulation, consistent with its association with obesity-related phenotypes.

AdipoUpX™ Human TFAP2B MSCV Particle (Overexpression)

Product Overview

Specification

Target Profile

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