AdipoUpX™ Human PRKAR1A Lentiviral Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human PRKAR1A Lentiviral Particle (Overexpression) is a powerful gene delivery tool specifically designed for the stable overexpression of the human PRKAR1A gene. As a regulatory subunit of protein kinase A, it is vital for researching lipolytic signaling and its dysregulation in Carney complex-associated metabolic phenotypes. All viral products undergo rigorous internal quality control to ensure reliability. Our customizable platform allows researchers to flexibly select from multiple promoters for precise targeted expression in various metabolic cell types.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: PCR analysis was performed to verify the complete genomic sequence of all viral vector preparations.

Sterility Test: This product was certified sterile following successful microbial growth analysis.

Mycoplasma Test: The production quality control confirmed the absence of any mycoplasmal agents.

Other QC: This comprehensive process includes customized supplementary testing alongside in vitro and in vivo transduction assessments to elucidate transgene expression and functionality.

Storage: To maintain product integrity, immediate transfer of the vector to a -80 °C is essential following its receipt.

Stability: Continuous storage at -80°C ensures excellent long-term stability for 6-12 months. Once thawed, the product's working solution should be refrigerated at 4°C and used within 2-3 weeks.

Shipping Condition: Our lentivirus viral products are shipped using dry ice.

Handling Notes: Ensure all operations are performed within a biosafety cabinet; upon receiving the vector, immediately aliquot it into low-protein-binding tubes and store according to specified conditions, thus avoiding the titer loss caused by sensitivity to temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application, despite our company's commitment to product quality and the rigorous internal QC inspections all products have undergone. Ultimate responsibility remains with the user for all operational processes, including storage, handling, and compliance with safety and biosafety protocols.

Target Profile

Gene Name: PRKAR1A

Full Name: Protein kinase cAMP-dependent type I regulatory subunit alpha

Gene Symbol: CAR; CNC; CNC1; PKR1; TSE1; ADOHR; PPNAD1; PRKAR1; ACRDYS1; Prkar1alpha

Gene ID: 5573

RefSeq ID-1: NP_001263218.1

RefSeq ID-2: NM_001276289.2

Summary: PRKAR1A encodes a regulatory subunit of protein kinase A, a central mediator of cAMP signaling. By modulating PKA activity, this protein influences hormone-responsive pathways involved in lipid mobilization, energy metabolism, and endocrine regulation. Disruption of PRKAR1A alters metabolic signaling dynamics.

AdipoUpX™ Human PRKAR1A Lentiviral Particle (Overexpression)

Product Overview

Specification

Target Profile

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