AdipoUpX™ Human PPY MSCV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human PPY MSCV Particle (Overexpression) provides a high-efficiency tool for the stable expression of pancreatic polypeptide, a key satiety-inducing hormone. This product is essential for research into the neuroendocrine regulation of food intake and gastrointestinal motility in obesity models. Optimized for stable expression in stem cells, hematopoietic stem cells, and other mammalian cell lines, the MSCV vector allows for flexible customization. All particles undergo exhaustive quality control—including sterility and titer assays—to ensure the safety and reproducibility of satiety signaling studies.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Final QC confirmed the correct molecular size and integrity of the insert through specific PCR amplification.

Sterility Test: No microbial contamination was detected in any product.

Mycoplasma Test: No mycoplasma presence was detected in this final viral preparation upon comprehensive testing.

Other QC: Our service scope includes both customized supplementary testing and comprehensive in vitro/in vivo transduction assessments.

Storage: The necessity of immediate transfer to -80 °C storage following receipt is crucial for upholding the product's integrity.

Stability: Biological activity remains intact for 6-12 months when stored at -80°C. Once removed from the freezer, the diluted working material is stable for up to 2-3 weeks at 4°C.

Shipping Condition: Our MSCV retroviral products are shipped using dry ice.

Handling Notes: Store the vector according to specified conditions and aliquot it immediately upon receipt into low-protein-binding tubes, which is necessary to maintain titer because viral particles are highly sensitive to both temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Throughout all operational processes, users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements. Although our company commits to product quality via rigorous internal QC inspections, the complexity of experimental conditions means we cannot guarantee product performance or experimental results in any specific application.

Target Profile

Gene Name: PPY

Full Name: Pancreatic polypeptide

Gene Symbol: PH; PP; PNP

Gene ID: 5539

RefSeq ID-1: NP_002713.1

RefSeq ID-2: NM_002722.5

Summary: PPY produces pancreatic polypeptide, a hormone synthesized in the islets of Langerhans that regulates gastrointestinal function and suppresses food intake. Reduced levels of PPY are associated with increased appetite, whereas its administration has been shown to decrease weight gain by signaling satiety to the brain.

AdipoUpX™ Human PPY MSCV Particle (Overexpression)

Product Overview

Specification

Target Profile

Related Products