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AdipoUpX™ Human PPY Lentiviral Particle (Overexpression)
Cat. No.:
V1225XX518
Species:
Human
Target Gene:
PPY
Vector System:
Lentiviral
Modulation Type:
Overexpression
SPECIFIC INQUIRY
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Product Overview
Description:
AdipoUpX™ Human PPY Lentiviral Particle (Overexpression) is professionally engineered for the efficient and long-lasting overexpression of the human PPY (Pancreatic Polypeptide) gene. This hormone is critical for investigating the regulation of food intake and gastric emptying. Every batch is verified through comprehensive quality control screening (titer, sterility, and mycoplasma), ensuring that experimental results are safe and high-fidelity. Our vector system offers high flexibility for the selection of reporter genes for precise longitudinal validation of satiety signaling.
Production Cell Line:
HEK293T
Promoter:
Ubi; CMV; EF1a; Others
Product Availability:
Produced Upon Order
Specification
Titer Test:
qPCR
Insert Verification:
PCR analysis was performed to verify the complete genomic sequence of all viral vector preparations.
Sterility Test:
This product was certified sterile following successful microbial growth analysis.
Mycoplasma Test:
The production quality control confirmed the absence of any mycoplasmal agents.
Other QC:
This comprehensive process includes customized supplementary testing alongside in vitro and in vivo transduction assessments to elucidate transgene expression and functionality.
Storage:
To maintain product integrity, immediate transfer of the vector to a -80 °C is essential following its receipt.
Stability:
Continuous storage at -80°C ensures excellent long-term stability for 6-12 months. Once thawed, the product's working solution should be refrigerated at 4°C and used within 2-3 weeks.
Shipping Condition:
Our lentivirus viral products are shipped using dry ice.
Handling Notes:
Ensure all operations are performed within a biosafety cabinet; upon receiving the vector, immediately aliquot it into low-protein-binding tubes and store according to specified conditions, thus avoiding the titer loss caused by sensitivity to temperature fluctuations and freeze-thaw cycles.
Intended Use:
This product is intended for research use only and is not for use in diagnosis or therapeutic applications.
Product Disclaimer:
Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application, despite our company's commitment to product quality and the rigorous internal QC inspections all products have undergone. Ultimate responsibility remains with the user for all operational processes, including storage, handling, and compliance with safety and biosafety protocols.
Target Profile
Gene Name:
PPY
Full Name:
Pancreatic polypeptide
Gene Symbol:
PH; PP; PNP
Gene ID:
5539
RefSeq ID-1:
NP_002713.1
RefSeq ID-2:
NM_002722.5
Summary:
PPY encodes pancreatic polypeptide, a hormone involved in the regulation of gastrointestinal activity and appetite. Circulating PPY levels correlate inversely with food intake, and experimental studies demonstrate its ability to suppress weight gain. The gene produces multiple transcript variants.