AdipoUpX™ Human OPA1 Lentiviral Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human OPA1 Lentiviral Particle (Overexpression) is a powerful gene delivery tool specifically designed for the stable overexpression of the human OPA1 gene. It is a critical tool for investigating mitochondrial cristae structure and fusion mechanisms in energy-expending tissues. Genome integration enables the establishment of stable cell lines for long-term functional studies. All viral particle products undergo rigorous internal quality control validation to ensure reliability, and the vector system is highly customizable for the inclusion of various fluorescent reporter genes.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: PCR analysis was performed to verify the complete genomic sequence of all viral vector preparations.

Sterility Test: This product was certified sterile following successful microbial growth analysis.

Mycoplasma Test: The production quality control confirmed the absence of any mycoplasmal agents.

Other QC: This comprehensive process includes customized supplementary testing alongside in vitro and in vivo transduction assessments to elucidate transgene expression and functionality.

Storage: To maintain product integrity, immediate transfer of the vector to a -80 °C is essential following its receipt.

Stability: Continuous storage at -80°C ensures excellent long-term stability for 6-12 months. Once thawed, the product's working solution should be refrigerated at 4°C and used within 2-3 weeks.

Shipping Condition: Our lentivirus viral products are shipped using dry ice.

Handling Notes: Ensure all operations are performed within a biosafety cabinet; upon receiving the vector, immediately aliquot it into low-protein-binding tubes and store according to specified conditions, thus avoiding the titer loss caused by sensitivity to temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application, despite our company's commitment to product quality and the rigorous internal QC inspections all products have undergone. Ultimate responsibility remains with the user for all operational processes, including storage, handling, and compliance with safety and biosafety protocols.

Target Profile

Gene Name: OPA1

Full Name: OPA1 mitochondrial dynamin like GTPase

Gene Symbol: NPG; NTG; MGM1; BERHS; largeG; MTDPS14

Gene ID: 4976

RefSeq ID-1: NP_056375.2

RefSeq ID-2: NM_015560.3

Summary: OPA1 encodes a mitochondrial dynamin-related GTPase that maintains inner mitochondrial membrane stability and energy production. Proper OPA1 function ensures efficient lipid oxidation and energy balance, with dysregulation potentially contributing to metabolic disorders and obesity.

AdipoUpX™ Human OPA1 Lentiviral Particle (Overexpression)

Product Overview

Specification

Target Profile

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