AdipoUpX™ Human MGLL Lentiviral Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human MGLL Lentiviral Particle (Overexpression) is professionally engineered for the efficient and stable expression of the human MGLL (Monoacylglycerol Lipase) gene. This enzyme is a key regulator of the endocannabinoid system and monoacylglycerol hydrolysis; its stable integration facilitates research into hunger signaling and energy intake. Genome integration enables the establishment of permanent cell models for functional studies. Every batch is verified through comprehensive quality control (titer, sterility, and mycoplasma) to ensure experimental safety.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: PCR analysis was performed to verify the complete genomic sequence of all viral vector preparations.

Sterility Test: This product was certified sterile following successful microbial growth analysis.

Mycoplasma Test: The production quality control confirmed the absence of any mycoplasmal agents.

Other QC: This comprehensive process includes customized supplementary testing alongside in vitro and in vivo transduction assessments to elucidate transgene expression and functionality.

Storage: To maintain product integrity, immediate transfer of the vector to a -80 °C is essential following its receipt.

Stability: Continuous storage at -80°C ensures excellent long-term stability for 6-12 months. Once thawed, the product's working solution should be refrigerated at 4°C and used within 2-3 weeks.

Shipping Condition: Our lentivirus viral products are shipped using dry ice.

Handling Notes: Ensure all operations are performed within a biosafety cabinet; upon receiving the vector, immediately aliquot it into low-protein-binding tubes and store according to specified conditions, thus avoiding the titer loss caused by sensitivity to temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application, despite our company's commitment to product quality and the rigorous internal QC inspections all products have undergone. Ultimate responsibility remains with the user for all operational processes, including storage, handling, and compliance with safety and biosafety protocols.

Target Profile

Gene Name: MGLL

Full Name: Monoglyceride lipase

Gene Symbol: MGL; HUK5; MAGL; HU-K5

Gene ID: 11343

RefSeq ID-1: NP_001003794.1

RefSeq ID-2: NM_001003794.3

Summary: MGLL encodes the enzyme responsible for breaking down monoacylglycerols into free fatty acids and glycerol. It is a dual-purpose regulator: it provides energy by mobilizing stored fats and also terminates signaling by the endocannabinoid 2-arachidonoylglycerol. This gives MGLL a unique role in linking fat metabolism to the regulation of pain and appetite.

AdipoUpX™ Human MGLL Lentiviral Particle (Overexpression)

Product Overview

Specification

Target Profile

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