AdipoUpX™ Human SLC2A4 Lentiviral Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human SLC2A4 Lentiviral Particle (Overexpression) is a powerful gene delivery tool specifically designed for the stable overexpression of the human SLC2A4 (GLUT4) gene. This glucose transporter is the endpoint for insulin action; establishing stable cell lines allows for high-fidelity research into glucose uptake mechanisms and insulin resistance. Every viral lot undergoes rigorous internal quality control (titer, sterility, and mycoplasma detection) to ensure safety and data integrity for metabolic studies.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: PCR analysis was performed to verify the complete genomic sequence of all viral vector preparations.

Sterility Test: This product was certified sterile following successful microbial growth analysis.

Mycoplasma Test: The production quality control confirmed the absence of any mycoplasmal agents.

Other QC: This comprehensive process includes customized supplementary testing alongside in vitro and in vivo transduction assessments to elucidate transgene expression and functionality.

Storage: To maintain product integrity, immediate transfer of the vector to a -80 °C is essential following its receipt.

Stability: Continuous storage at -80°C ensures excellent long-term stability for 6-12 months. Once thawed, the product's working solution should be refrigerated at 4°C and used within 2-3 weeks.

Shipping Condition: Our lentivirus viral products are shipped using dry ice.

Handling Notes: Ensure all operations are performed within a biosafety cabinet; upon receiving the vector, immediately aliquot it into low-protein-binding tubes and store according to specified conditions, thus avoiding the titer loss caused by sensitivity to temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application, despite our company's commitment to product quality and the rigorous internal QC inspections all products have undergone. Ultimate responsibility remains with the user for all operational processes, including storage, handling, and compliance with safety and biosafety protocols.

Target Profile

Gene Name: SLC2A4

Full Name: Solute carrier family 2 member 4

Gene Symbol: GLUT4

Gene ID: 6517

RefSeq ID-1: NP_001033.1

RefSeq ID-2: NM_001042.3

Summary: SLC2A4 encodes an insulin-sensitive glucose transporter, primarily expressed in muscle and adipose tissues. In the absence of insulin, the protein is retained intracellularly, but insulin stimulation triggers its translocation to the cell membrane, enabling glucose uptake. Mutations in this gene are associated with noninsulin-dependent diabetes mellitus (NIDDM).

AdipoUpX™ Human SLC2A4 Lentiviral Particle (Overexpression)

Product Overview

Specification

Target Profile

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