AdipoUpX™ Human STEAP4 Lentiviral Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human STEAP4 Lentiviral Particle (Overexpression) is a ready-to-use, high-titer vector particle professionally engineered for the stable overexpression of the human STEAP4 gene. As a metalloreductase localized to the trans-Golgi network and plasma membrane, it plays a vital role in protecting adipocytes against inflammation and oxidative stress. Genome integration ensures the target gene integrates into the host cell genome, establishing reliable, stable cell lines for long-term metabolic study. To ensure the highest research standards, the product undergoes comprehensive quality control, including titer, sterility, and mycoplasma testing.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: PCR analysis was performed to verify the complete genomic sequence of all viral vector preparations.

Sterility Test: This product was certified sterile following successful microbial growth analysis.

Mycoplasma Test: The production quality control confirmed the absence of any mycoplasmal agents.

Other QC: This comprehensive process includes customized supplementary testing alongside in vitro and in vivo transduction assessments to elucidate transgene expression and functionality.

Storage: To maintain product integrity, immediate transfer of the vector to a -80 °C is essential following its receipt.

Stability: Continuous storage at -80°C ensures excellent long-term stability for 6-12 months. Once thawed, the product's working solution should be refrigerated at 4°C and used within 2-3 weeks.

Shipping Condition: Our lentivirus viral products are shipped using dry ice.

Handling Notes: Ensure all operations are performed within a biosafety cabinet; upon receiving the vector, immediately aliquot it into low-protein-binding tubes and store according to specified conditions, thus avoiding the titer loss caused by sensitivity to temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application, despite our company's commitment to product quality and the rigorous internal QC inspections all products have undergone. Ultimate responsibility remains with the user for all operational processes, including storage, handling, and compliance with safety and biosafety protocols.

Target Profile

Gene Name: STEAP4

Full Name: STEAP4 metalloreductase

Gene Symbol: TIARP; STAMP2; SchLAH; TNFAIP9

Gene ID: 79689

RefSeq ID-1: NP_001192244.1

RefSeq ID-2: NM_001205315.2

Summary: STEAP4 encodes a Golgi-localized metalloreductase that plays a vital role in cellular mineral balance by reducing ferric iron and cupric copper. Beyond its enzymatic function, it is a key participant in adipocyte metabolism and development. By managing metal ion states, STEAP4 influences the oxidative environment of fat cells and is implicated in both normal prostate biology and the progression of certain cancers.

AdipoUpX™ Human STEAP4 Lentiviral Particle (Overexpression)

Product Overview

Specification

Target Profile

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