AdipoUpX™ Human PPARA Lentiviral Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human PPARA Lentiviral Particle (Overexpression) is professionally engineered for the efficient and stable expression of the human PPARA gene. As a master transcription factor for fatty acid oxidation, it is a reliable asset for researching lipid-lowering therapies and energy metabolism. The lentivirus characteristic of genome integration establishes permanent cell models for functional studies. Every batch is verified through comprehensive quality control screening (titer, sterility, and mycoplasma), ensuring repeatable and safe experimental results.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: PCR analysis was performed to verify the complete genomic sequence of all viral vector preparations.

Sterility Test: This product was certified sterile following successful microbial growth analysis.

Mycoplasma Test: The production quality control confirmed the absence of any mycoplasmal agents.

Other QC: This comprehensive process includes customized supplementary testing alongside in vitro and in vivo transduction assessments to elucidate transgene expression and functionality.

Storage: To maintain product integrity, immediate transfer of the vector to a -80 °C is essential following its receipt.

Stability: Continuous storage at -80°C ensures excellent long-term stability for 6-12 months. Once thawed, the product's working solution should be refrigerated at 4°C and used within 2-3 weeks.

Shipping Condition: Our lentivirus viral products are shipped using dry ice.

Handling Notes: Ensure all operations are performed within a biosafety cabinet; upon receiving the vector, immediately aliquot it into low-protein-binding tubes and store according to specified conditions, thus avoiding the titer loss caused by sensitivity to temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application, despite our company's commitment to product quality and the rigorous internal QC inspections all products have undergone. Ultimate responsibility remains with the user for all operational processes, including storage, handling, and compliance with safety and biosafety protocols.

Target Profile

Gene Name: PPARA

Full Name: Peroxisome proliferator activated receptor alpha

Gene Symbol: PPAR; NR1C1; hPPAR; PPARalpha; PPAR-alpha

Gene ID: 5465

RefSeq ID-1: NP_001001928.1

RefSeq ID-2: NM_001001928.4

Summary: PPARA encodes peroxisome proliferator-activated receptor alpha, a nuclear receptor that regulates genes involved in lipid metabolism, cell differentiation, proliferation, and immune responses. PPARα is activated by peroxisome proliferators, including hypolipidemic drugs, herbicides, and leukotriene antagonists. Several transcript variants have been reported, with two full-length isoforms fully characterized.

AdipoUpX™ Human PPARA Lentiviral Particle (Overexpression)

Product Overview

Specification

Target Profile

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