AdipoUpX™ Human GATA3 Lentiviral Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human GATA3 Lentiviral Particle (Overexpression) is a high-titer system for the specific and stable expression of the human GATA3 gene. As a potent inhibitor of adipocyte differentiation, its stable overexpression is an ideal tool for researching the maintenance of the pre-adipocyte state and the prevention of hyperplastic obesity. All viral products undergo rigorous internal quality control to ensure reliability and safety. Clients can freely customize key functional components to match their unique experimental needs and cell-specific models.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: PCR analysis was performed to verify the complete genomic sequence of all viral vector preparations.

Sterility Test: This product was certified sterile following successful microbial growth analysis.

Mycoplasma Test: The production quality control confirmed the absence of any mycoplasmal agents.

Other QC: This comprehensive process includes customized supplementary testing alongside in vitro and in vivo transduction assessments to elucidate transgene expression and functionality.

Storage: To maintain product integrity, immediate transfer of the vector to a -80 °C is essential following its receipt.

Stability: Continuous storage at -80°C ensures excellent long-term stability for 6-12 months. Once thawed, the product's working solution should be refrigerated at 4°C and used within 2-3 weeks.

Shipping Condition: Our lentivirus viral products are shipped using dry ice.

Handling Notes: Ensure all operations are performed within a biosafety cabinet; upon receiving the vector, immediately aliquot it into low-protein-binding tubes and store according to specified conditions, thus avoiding the titer loss caused by sensitivity to temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application, despite our company's commitment to product quality and the rigorous internal QC inspections all products have undergone. Ultimate responsibility remains with the user for all operational processes, including storage, handling, and compliance with safety and biosafety protocols.

Target Profile

Gene Name: GATA3

Full Name: GATA binding protein 3

Gene Symbol: HDR; HDRS

Gene ID: 2625

RefSeq ID-1: NP_001002295.1

RefSeq ID-2: NM_001002295.2

Summary: GATA3 is a zinc-finger transcription factor that serves as a master regulator of T-cell identity and endothelial cell health. While primarily known for its role in the immune system, its influence on the vascular endothelium is critical for maintaining the healthy blood flow and nutrient exchange required for balanced systemic metabolism.

AdipoUpX™ Human GATA3 Lentiviral Particle (Overexpression)

Product Overview

Specification

Target Profile

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