AdipoUpX™ Human ELOVL6 Lentiviral Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human ELOVL6 Lentiviral Particle (Overexpression) is a high-titer system for the specific and stable expression of the human ELOVL6 gene. This elongase is responsible for converting palmitate to stearate, a critical step in determining the fatty acid composition of tissues and insulin sensitivity. All viral particle products undergo comprehensive quality control to ensure safety and efficacy. Clients can freely customize key functional components to match their unique experimental needs and lipidomic research models.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: PCR analysis was performed to verify the complete genomic sequence of all viral vector preparations.

Sterility Test: This product was certified sterile following successful microbial growth analysis.

Mycoplasma Test: The production quality control confirmed the absence of any mycoplasmal agents.

Other QC: This comprehensive process includes customized supplementary testing alongside in vitro and in vivo transduction assessments to elucidate transgene expression and functionality.

Storage: To maintain product integrity, immediate transfer of the vector to a -80 °C is essential following its receipt.

Stability: Continuous storage at -80°C ensures excellent long-term stability for 6-12 months. Once thawed, the product's working solution should be refrigerated at 4°C and used within 2-3 weeks.

Shipping Condition: Our lentivirus viral products are shipped using dry ice.

Handling Notes: Ensure all operations are performed within a biosafety cabinet; upon receiving the vector, immediately aliquot it into low-protein-binding tubes and store according to specified conditions, thus avoiding the titer loss caused by sensitivity to temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application, despite our company's commitment to product quality and the rigorous internal QC inspections all products have undergone. Ultimate responsibility remains with the user for all operational processes, including storage, handling, and compliance with safety and biosafety protocols.

Target Profile

Gene Name: ELOVL6

Full Name: ELOVL fatty acid elongase 6

Gene Symbol: FAE; LCE; FACE; hELO2

Gene ID: 79071

RefSeq ID-1: NP_001124193.1

RefSeq ID-2: NM_001130721.2

Summary: ELOVL6 encodes a fatty acid elongase that catalyzes the rate-limiting step of elongating saturated and monounsaturated fatty acids using malonyl-CoA as a two-carbon donor. ELOVL6 activity directly affects fatty acid composition in liver and adipose tissue and has been linked to insulin sensitivity, hepatic steatosis, and obesity-associated metabolic dysfunction.

AdipoUpX™ Human ELOVL6 Lentiviral Particle (Overexpression)

Product Overview

Specification

Target Profile

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