AdipoUpX™ Human RBP4 Lentiviral Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human RBP4 Lentiviral Particle (Overexpression) is professionally engineered for the long-lasting, stable overexpression of the human RBP4 gene. As a major adipokine linked to insulin resistance, its stable expression in cell models allows for systematic investigation into glucose transport inhibition. The product is ready-to-use and high-titer, with safety and efficacy guaranteed by rigorous internal QC, including sterility and mycoplasma testing. Clients can freely select reporter genes to monitor RBP4 secretion and its impact on metabolic signaling pathways.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: PCR analysis was performed to verify the complete genomic sequence of all viral vector preparations.

Sterility Test: This product was certified sterile following successful microbial growth analysis.

Mycoplasma Test: The production quality control confirmed the absence of any mycoplasmal agents.

Other QC: This comprehensive process includes customized supplementary testing alongside in vitro and in vivo transduction assessments to elucidate transgene expression and functionality.

Storage: To maintain product integrity, immediate transfer of the vector to a -80 °C is essential following its receipt.

Stability: Continuous storage at -80°C ensures excellent long-term stability for 6-12 months. Once thawed, the product's working solution should be refrigerated at 4°C and used within 2-3 weeks.

Shipping Condition: Our lentivirus viral products are shipped using dry ice.

Handling Notes: Ensure all operations are performed within a biosafety cabinet; upon receiving the vector, immediately aliquot it into low-protein-binding tubes and store according to specified conditions, thus avoiding the titer loss caused by sensitivity to temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application, despite our company's commitment to product quality and the rigorous internal QC inspections all products have undergone. Ultimate responsibility remains with the user for all operational processes, including storage, handling, and compliance with safety and biosafety protocols.

Target Profile

Gene Name: RBP4

Full Name: Retinol binding protein 4

Gene Symbol: RDCCAS; MCOPCB10

Gene ID: 5950

RefSeq ID-1: NP_001310446.1

RefSeq ID-2: NM_001323517.1

Summary: RBP4 belongs to the lipocalin family and serves as the specific carrier protein for retinol (Vitamin A alcohol) in the bloodstream. Its primary function is to transport retinol from the liver storage sites to various peripheral tissues throughout the body. In plasma, the RBP4-retinol complex associates with transthyretin, which is necessary to prevent the complex from being rapidly filtered out and lost via the kidney glomeruli. RBP4 levels have been strongly linked to insulin resistance and Type 2 diabetes, and elevated circulating RBP4 has been observed in individuals with obesity.

AdipoUpX™ Human RBP4 Lentiviral Particle (Overexpression)

Product Overview

Specification

Target Profile

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