AdipoUpX™ Human EIF2S3 Lentiviral Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human EIF2S3 Lentiviral Particle (Overexpression) is a ready-to-use, high-titer vector particle designed for the efficient and stable overexpression of the human EIF2S3 gene. Linked to glucose intolerance and developmental syndromes, its stable integration into the host genome provides a reliable platform for researching translational control in metabolic health. Every batch undergoes rigorous quality control, including titer and mycoplasma testing, ensuring experimental safety. Researchers can flexibly customize promoters and labels for precise targeted delivery.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: PCR analysis was performed to verify the complete genomic sequence of all viral vector preparations.

Sterility Test: This product was certified sterile following successful microbial growth analysis.

Mycoplasma Test: The production quality control confirmed the absence of any mycoplasmal agents.

Other QC: This comprehensive process includes customized supplementary testing alongside in vitro and in vivo transduction assessments to elucidate transgene expression and functionality.

Storage: To maintain product integrity, immediate transfer of the vector to a -80 °C is essential following its receipt.

Stability: Continuous storage at -80°C ensures excellent long-term stability for 6-12 months. Once thawed, the product's working solution should be refrigerated at 4°C and used within 2-3 weeks.

Shipping Condition: Our lentivirus viral products are shipped using dry ice.

Handling Notes: Ensure all operations are performed within a biosafety cabinet; upon receiving the vector, immediately aliquot it into low-protein-binding tubes and store according to specified conditions, thus avoiding the titer loss caused by sensitivity to temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application, despite our company's commitment to product quality and the rigorous internal QC inspections all products have undergone. Ultimate responsibility remains with the user for all operational processes, including storage, handling, and compliance with safety and biosafety protocols.

Target Profile

Gene Name: EIF2S3

Full Name: Eukaryotic translation initiation factor 2 subunit gamma

Gene Symbol: EIF2; EIF2G; MEHMO; eIF2gX; MRXSBRK; eIF-2gA; EIF2gamma

Gene ID: 1968

RefSeq ID-1: NP_001406.1

RefSeq ID-2: NM_001415.4

Summary: EIF2S3 encodes the largest component of the eIF2 complex, a heterotrimeric GTP-binding protein essential for protein synthesis. It plays a "gatekeeper" role by recruiting the initiator methionyl-tRNA to the ribosome. While fundamental to general cell biology, its role in protein translation makes it a factor in how cells respond to metabolic stress and growth signals, with mutations potentially impacting systemic development.

AdipoUpX™ Human EIF2S3 Lentiviral Particle (Overexpression)

Product Overview

Specification

Target Profile

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