AdipoUpX™ Human ACSL4 Lentiviral Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human ACSL4 Lentiviral Particle (Overexpression) is a high-titer system for the specific and stable expression of the human ACSL4 gene. This enzyme is critical for the activation of long-chain fatty acids, making it a powerful asset for studying polyunsaturated fatty acid metabolism and ferroptosis in metabolic contexts. Our vector system features a modular design for easy customization of markers and labels. All products undergo comprehensive quality control to ensure experimental safety and the reproducibility of results through genome-integrated stable expression.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: PCR analysis was performed to verify the complete genomic sequence of all viral vector preparations.

Sterility Test: This product was certified sterile following successful microbial growth analysis.

Mycoplasma Test: The production quality control confirmed the absence of any mycoplasmal agents.

Other QC: This comprehensive process includes customized supplementary testing alongside in vitro and in vivo transduction assessments to elucidate transgene expression and functionality.

Storage: To maintain product integrity, immediate transfer of the vector to a -80 °C is essential following its receipt.

Stability: Continuous storage at -80°C ensures excellent long-term stability for 6-12 months. Once thawed, the product's working solution should be refrigerated at 4°C and used within 2-3 weeks.

Shipping Condition: Our lentivirus viral products are shipped using dry ice.

Handling Notes: Ensure all operations are performed within a biosafety cabinet; upon receiving the vector, immediately aliquot it into low-protein-binding tubes and store according to specified conditions, thus avoiding the titer loss caused by sensitivity to temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application, despite our company's commitment to product quality and the rigorous internal QC inspections all products have undergone. Ultimate responsibility remains with the user for all operational processes, including storage, handling, and compliance with safety and biosafety protocols.

Target Profile

Gene Name: ACSL4

Full Name: Acyl-CoA synthetase long chain family member 4

Gene Symbol: ACS4; FACL4; LACS4; MRX63; MRX68; XLID63

Gene ID: 2182

RefSeq ID-1: NP_001305438.1

RefSeq ID-2: NM_001318509.2

Summary: ACSL4 encodes a long-chain fatty-acid-CoA ligase that preferentially activates arachidonic acid. By converting free fatty acids into acyl-CoA esters, ACSL4 plays a key role in lipid synthesis and degradation, affecting adipocyte lipid storage and energy balance. Alternative splicing produces multiple transcript variants.

AdipoUpX™ Human ACSL4 Lentiviral Particle (Overexpression)

Product Overview

Specification

Target Profile

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