AdipoUpX™ Human DGAT2 Lentiviral Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human DGAT2 Lentiviral Particle (Overexpression) is a high-titer system for the specific and stable expression of the human DGAT2 gene. As a primary enzyme for triglyceride synthesis, its stable overexpression is essential for researching the final steps of lipid storage and the prevention of hepatic steatosis. The lentivirus characteristic of genome integration establishes reliable cell models for high-throughput metabolic screening. Comprehensive quality control is performed on all viral particle products to ensure both product safety and the reproducibility of your data.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: PCR analysis was performed to verify the complete genomic sequence of all viral vector preparations.

Sterility Test: This product was certified sterile following successful microbial growth analysis.

Mycoplasma Test: The production quality control confirmed the absence of any mycoplasmal agents.

Other QC: This comprehensive process includes customized supplementary testing alongside in vitro and in vivo transduction assessments to elucidate transgene expression and functionality.

Storage: To maintain product integrity, immediate transfer of the vector to a -80 °C is essential following its receipt.

Stability: Continuous storage at -80°C ensures excellent long-term stability for 6-12 months. Once thawed, the product's working solution should be refrigerated at 4°C and used within 2-3 weeks.

Shipping Condition: Our lentivirus viral products are shipped using dry ice.

Handling Notes: Ensure all operations are performed within a biosafety cabinet; upon receiving the vector, immediately aliquot it into low-protein-binding tubes and store according to specified conditions, thus avoiding the titer loss caused by sensitivity to temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application, despite our company's commitment to product quality and the rigorous internal QC inspections all products have undergone. Ultimate responsibility remains with the user for all operational processes, including storage, handling, and compliance with safety and biosafety protocols.

Target Profile

Gene Name: DGAT2

Full Name: Diacylglycerol O-acyltransferase 2

Gene Symbol: ARAT; HMFN1045; GS1999FULL

Gene ID: 84649

RefSeq ID-1: NP_001240820.1

RefSeq ID-2: NM_001253891.2

Summary: DGAT2 encodes an enzyme catalyzing the final step of triglyceride synthesis, directly controlling fat storage in adipocytes. Its activity influences energy storage efficiency and susceptibility to obesity. Multiple transcript variants exist due to alternative splicing.

AdipoUpX™ Human DGAT2 Lentiviral Particle (Overexpression)

Product Overview

Specification

Target Profile

Related Products