AdipoUpX™ Human CIDEA Lentiviral Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human CIDEA Lentiviral Particle (Overexpression) is professionally engineered for the efficient and long-lasting overexpression of the human CIDEA gene. This cell death-inducing DFFA-like effector is a key regulator of lipid droplet size and thermogenesis, making this stable integration tool ideal for studying fat storage mechanisms. Every viral batch is verified through comprehensive quality control (titer, sterility, and mycoplasma detection) to ensure the highest standards. The lentivirus characteristic of genome integration establishes reliable cell models for high-fidelity metabolic studies.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: PCR analysis was performed to verify the complete genomic sequence of all viral vector preparations.

Sterility Test: This product was certified sterile following successful microbial growth analysis.

Mycoplasma Test: The production quality control confirmed the absence of any mycoplasmal agents.

Other QC: This comprehensive process includes customized supplementary testing alongside in vitro and in vivo transduction assessments to elucidate transgene expression and functionality.

Storage: To maintain product integrity, immediate transfer of the vector to a -80 °C is essential following its receipt.

Stability: Continuous storage at -80°C ensures excellent long-term stability for 6-12 months. Once thawed, the product's working solution should be refrigerated at 4°C and used within 2-3 weeks.

Shipping Condition: Our lentivirus viral products are shipped using dry ice.

Handling Notes: Ensure all operations are performed within a biosafety cabinet; upon receiving the vector, immediately aliquot it into low-protein-binding tubes and store according to specified conditions, thus avoiding the titer loss caused by sensitivity to temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application, despite our company's commitment to product quality and the rigorous internal QC inspections all products have undergone. Ultimate responsibility remains with the user for all operational processes, including storage, handling, and compliance with safety and biosafety protocols.

Target Profile

Gene Name: CIDEA

Full Name: Cell death inducing DFFA like effector a

Gene Symbol: CIDE-A

Gene ID: 1149

RefSeq ID-1: NP_001270.1

RefSeq ID-2: NM_001279.4

Summary: CIDEA acts as a major regulator of energy expenditure and fat accumulation. In animal models, the absence of CIDEA leads to an increased metabolic rate and enhanced thermogenesis in brown adipose tissue, conferring resistance to diet-induced obesity. While it shares structural homology with cell death-inducing factors, its primary physiological impact lies in modulating lipolysis and core body temperature during cold exposure.

AdipoUpX™ Human CIDEA Lentiviral Particle (Overexpression)

Product Overview

Specification

Target Profile

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