AdipoUpX™ Human ADIPOR1 Lentiviral Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human ADIPOR1 Lentiviral Particle (Overexpression) is a ready-to-use, high-titer vector particle professionally engineered for the specific and long-lasting stable overexpression of the human ADIPOR1 gene. As a primary receptor for adiponectin, its stable integration into the host genome is essential for researching AMPK activation and glucose uptake in insulin-sensitive tissues. To ensure experimental reproducibility and safety, every batch undergoes comprehensive quality control, including titer, sterility, and mycoplasma testing. Our modular system provides high flexibility for the customization of cell-specific promoters and fluorescent markers.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: PCR analysis was performed to verify the complete genomic sequence of all viral vector preparations.

Sterility Test: This product was certified sterile following successful microbial growth analysis.

Mycoplasma Test: The production quality control confirmed the absence of any mycoplasmal agents.

Other QC: This comprehensive process includes customized supplementary testing alongside in vitro and in vivo transduction assessments to elucidate transgene expression and functionality.

Storage: To maintain product integrity, immediate transfer of the vector to a -80 °C is essential following its receipt.

Stability: Continuous storage at -80°C ensures excellent long-term stability for 6-12 months. Once thawed, the product's working solution should be refrigerated at 4°C and used within 2-3 weeks.

Shipping Condition: Our lentivirus viral products are shipped using dry ice.

Handling Notes: Ensure all operations are performed within a biosafety cabinet; upon receiving the vector, immediately aliquot it into low-protein-binding tubes and store according to specified conditions, thus avoiding the titer loss caused by sensitivity to temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application, despite our company's commitment to product quality and the rigorous internal QC inspections all products have undergone. Ultimate responsibility remains with the user for all operational processes, including storage, handling, and compliance with safety and biosafety protocols.

Target Profile

Gene Name: ADIPOR1

Full Name: Adiponectin receptor 1

Gene Symbol: CGI45; PAQR1; ACDCR1; CGI-45; TESBP1A

Gene ID: 51094

RefSeq ID-1: NP_001277482.1

RefSeq ID-2: NM_001290553.2

Summary: ADIPOR1 encodes an adiponectin-responsive receptor that mediates key metabolic actions of this adipocyte-derived hormone. Upon ligand binding, ADIPOR1 activates AMPK-dependent signaling cascades that enhance fatty acid oxidation and improve insulin responsiveness. Through these mechanisms, ADIPOR1 contributes to the regulation of systemic energy balance and obesity-related metabolic traits.

AdipoUpX™ Human ADIPOR1 Lentiviral Particle (Overexpression)

Product Overview

Specification

Target Profile

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