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Methylprednisolone (NSC-19987)
Cat. No.:
OB0225WX-2441
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
Add to basket
Product Overview
Description:
Methylprednisolone (NSC-19987) is a synthetic agonist of the glucocorticoid receptor that acts at the molecular level to activate ACE2 and suppress IL-6 levels, while also functioning as a negative regulator of autophagy and apoptosis.
Synonym:
NSC-19987; U 7532; 83-43-2; Methylprednisolone; Medrol; Metilprednisolone; Medrone; 6alpha-Methylprednisolone; Metilbetasone; Medrate; Urbason; Dopomedrol; Medesone; Mesopren; Metastab; Metrisone; Noretona; Promacortine; Urbasone; Besonia; Moderin; Solomet; Wyacort; Methylprednisolon; Sieropresol; Suprametil; Esametone; Firmacort; Medixon; Metrocort; Metysolon; Nirypan; Reactenol; Lemod; Artisone-wyeth; Medrol dosepak; Methyleneprednisolone; Medrol adt pak; Predni N Tablinen; 6-alpha-Methylprednisolone; Metilprednisolona; delta(1)-6alpha-Methylhydrocortisone; 1-Dehydro-6alpha-methylhydrocortisone; Methylprednisolonum; Summicort; Prednisolone, methyl-; 6-methyl-prednisolone; Prednisolone, 6alpha-methyl-; 11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione; 6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione; Delta(sup 1)-6-alpha-Methylhydrocortisone; (6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one; Methylprednisolone, 6-alpha; 11beta,17alpha,21-Trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione; Methylprednisolone (Standard); (6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione; (6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
CAS No.:
83-43-2
Compound CID:
6741
Formula:
C22H30O5
Formula Weight:
374.47
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Methylprednisolone (NSC-19987) is utilized in immunological research as a potent glucocorticoid to investigate the suppression of cytokine storms and the regulation of gene expression in acute inflammatory models.
Library Information
Target:
ACE; Glucocorticoid receptor; Interleukin
Pathways:
Endocrinology & Hormones
Plate Number:
L6700-02
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
75 mg/mL; 200.28 mM
Ethanol Max Solubility:
2 mg/mL
ALogP:
1.512
HBA_Count:
2
HBD_Count:
2
Rotatable Bond:
2





