LipoKnoxa™ Human SLC2A4 shRNA Lentiviral Particle (Silencing)

Sub Cat. No.	TargetSeq	Region	Inquiry
V0126XX507-1	GCCCTACGTCTTCCTTCTATT	CDS	Inquiry
V0126XX507-2	TGATTGAACAGAGCTACAATG	CDS	Inquiry
V0126XX507-3	GGAGACAAGAAATCCAGTTTC	3' UTR	Inquiry
V0126XX507-4	Other		Inquiry

Product Overview

Description: LipoKnoxa™ Human SLC2A4 shRNA Lentiviral Particle (Silencing) focuses on the inhibition of the GLUT4 transporter, essential for insulin-responsive glucose uptake. By utilizing optimized U6 and miR30-based shRNA delivery, this tool assists in uncovering the pathways of glucose disposal in muscle and adipocytes, etc. Each batch is validated through stringent QC processes, including functional titering and microbial safety checks.

Production Cell Line: HEK293T

Promoter: U6; CMV; EF1α; CAG; UBC

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Comprehensive sequencing and PCR analyses were performed to verify the accurate genomic sequence of all viral preparations.

Sterility Test: Confirmed sterile via rigorous microbial analysis; free of bacterial and fungal contamination.

Mycoplasma Test: Rigorous quality control testing has confirmed the absence of mycoplasma contamination in this viral preparation.

Other QC: Customized supplementary testing and in vitro/in vivo assessments are available to verify post-silencing gene expression and biological functionality, ensuring the viral preparations meet the specific potency requirements of your gene interference project.

Storage: Store at -80°C for long-term preservation. Immediate transfer upon delivery is required to prevent loss of viral activity.

Stability: Shelf life: 6–12 months at -80°C (extended stability up to 2 years). Post-thaw: Stable at 4°C for 2–3 weeks without significant degradation of functional titers.

Shipping Condition: Products are delivered on dry ice to maintain the cold chain. Upon arrival, please ensure the presence of dry ice and transfer the vials immediately to -80°C storage.

Handling Notes: Avoid repeated freeze-thaw cycles. Aliquot into low-protein-binding tubes immediately after receipt to maintain optimal activity. For safety and contamination control, all viral handling must be performed inside a biosafety cabinet.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: We ensure product integrity through rigorous QC, but we do not guarantee results in specific research contexts. Proper storage, handling, and total compliance with biosafety laws and safety protocols remain the sole responsibility of the user.

Target Profile

Gene Name: SLC2A4

Full Name: Solute carrier family 2 member 4

Gene Symbol: GLUT4

Gene ID: 6517

RefSeq ID-1: NP_001033.1

RefSeq ID-2: NM_001042.3

Summary: SLC2A4 encodes an insulin-sensitive glucose transporter, primarily expressed in muscle and adipose tissues. In the absence of insulin, the protein is retained intracellularly, but insulin stimulation triggers its translocation to the cell membrane, enabling glucose uptake. Mutations in this gene are associated with noninsulin-dependent diabetes mellitus (NIDDM).

LipoKnoxa™ Human SLC2A4 shRNA Lentiviral Particle (Silencing)

Product Overview

Specification

Target Profile

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