AdipoUpX™ Human KCTD15 Lentiviral Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human KCTD15 Lentiviral Particle (Overexpression) is a powerful, high-titer gene delivery tool specifically designed for the stable overexpression of the human KCTD15 gene. Genome integration enables the establishment of stable cell lines to investigate its role as a suppressor of AP-2 transcription factors and its influence on adipogenesis. To ensure safety and efficacy, all particles undergo comprehensive quality control screening. This product accelerates progress in metabolic research by allowing researchers to flexibly select reporter genes for long-term functional validation.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: PCR analysis was performed to verify the complete genomic sequence of all viral vector preparations.

Sterility Test: This product was certified sterile following successful microbial growth analysis.

Mycoplasma Test: The production quality control confirmed the absence of any mycoplasmal agents.

Other QC: This comprehensive process includes customized supplementary testing alongside in vitro and in vivo transduction assessments to elucidate transgene expression and functionality.

Storage: To maintain product integrity, immediate transfer of the vector to a -80 °C is essential following its receipt.

Stability: Continuous storage at -80°C ensures excellent long-term stability for 6-12 months. Once thawed, the product's working solution should be refrigerated at 4°C and used within 2-3 weeks.

Shipping Condition: Our lentivirus viral products are shipped using dry ice.

Handling Notes: Ensure all operations are performed within a biosafety cabinet; upon receiving the vector, immediately aliquot it into low-protein-binding tubes and store according to specified conditions, thus avoiding the titer loss caused by sensitivity to temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application, despite our company's commitment to product quality and the rigorous internal QC inspections all products have undergone. Ultimate responsibility remains with the user for all operational processes, including storage, handling, and compliance with safety and biosafety protocols.

Target Profile

Gene Name: KCTD15

Full Name: Potassium channel tetramerization domain containing 15

Gene ID: 79047

RefSeq ID-1: NP_001123466.1

RefSeq ID-2: NM_001129994.2

Summary: KCTD15 is a nuclear protein characterized by its ability to engage in identical protein binding. Functional predictions suggest it acts as a negative regulator of DNA-templated transcription, potentially silencing gene sets involved in neural development. Significant genome-wide association studies have identified KCTD15 as a key locus associated with increased body mass index (BMI) and adiposity in humans.

AdipoUpX™ Human KCTD15 Lentiviral Particle (Overexpression)

Product Overview

Specification

Target Profile

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