LipoKnoxa™ Human PPARD shRNA Lentiviral Particle (Silencing)

Sub Cat. No.	TargetSeq	Region	Inquiry
V0126XX536-1	CCGCAAACCCTTCAGTGATAT	CDS	Inquiry
V0126XX536-2	TATTCATTGCGGCCATCATTC	CDS	Inquiry
V0126XX536-3	ATCCACGACATCGAGACATTG	CDS	Inquiry
V0126XX536-4	Other		Inquiry

Product Overview

Description: LipoKnoxa™ Human PPARD shRNA Lentiviral Particle (Silencing) targets PPAR-delta, which promotes fatty acid burning in muscle. Our lentiviral system supports both U6 and miR30-based shRNA strategies, offering flexible options for long-term silencing. Each batch is subjected to rigorous quality control, including high-precision functional titering and sterility testing.

Production Cell Line: HEK293T

Promoter: U6; CMV; EF1α; CAG; UBC

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Comprehensive sequencing and PCR analyses were performed to verify the accurate genomic sequence of all viral preparations.

Sterility Test: Confirmed sterile via rigorous microbial analysis; free of bacterial and fungal contamination.

Mycoplasma Test: Rigorous quality control testing has confirmed the absence of mycoplasma contamination in this viral preparation.

Other QC: Customized supplementary testing and in vitro/in vivo assessments are available to verify post-silencing gene expression and biological functionality, ensuring the viral preparations meet the specific potency requirements of your gene interference project.

Storage: Store at -80°C for long-term preservation. Immediate transfer upon delivery is required to prevent loss of viral activity.

Stability: Shelf life: 6–12 months at -80°C (extended stability up to 2 years). Post-thaw: Stable at 4°C for 2–3 weeks without significant degradation of functional titers.

Shipping Condition: Products are delivered on dry ice to maintain the cold chain. Upon arrival, please ensure the presence of dry ice and transfer the vials immediately to -80°C storage.

Handling Notes: Avoid repeated freeze-thaw cycles. Aliquot into low-protein-binding tubes immediately after receipt to maintain optimal activity. For safety and contamination control, all viral handling must be performed inside a biosafety cabinet.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: We ensure product integrity through rigorous QC, but we do not guarantee results in specific research contexts. Proper storage, handling, and total compliance with biosafety laws and safety protocols remain the sole responsibility of the user.

Target Profile

Gene Name: PPARD

Full Name: Peroxisome proliferator activated receptor delta

Gene Symbol: FAAR; NUC1; NUCI; NR1C2; NUCII; PPARB

Gene ID: 5467

RefSeq ID-1: NP_001165289.1

RefSeq ID-2: NM_001171818.2

Summary: PPARD encodes a nuclear receptor of the PPAR family that regulates transcriptional programs involved in lipid metabolism and energy utilization. The protein influences fatty acid oxidation, cellular differentiation, and metabolic flexibility. Experimental models suggest PPARD activity impacts body composition and susceptibility to metabolic disease.

LipoKnoxa™ Human PPARD shRNA Lentiviral Particle (Silencing)

Product Overview

Specification

Target Profile

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