LipoKnoxa™ Human ANGPTL6 shRNA Lentiviral Particle (Silencing)

Sub Cat. No.	TargetSeq	Region	Inquiry
V0126XX628-1	GTTCTGGCCACACCTTCTTTG	3' UTR	Inquiry
V0126XX628-2	TGATGCTGGAGACTCTCTTTC	CDS	Inquiry
V0126XX628-3	GAACAGAGTGGAGTGTATGAA	CDS	Inquiry
V0126XX628-4	Other		Inquiry

Product Overview

Description: LipoKnoxa™ Human ANGPTL6 shRNA Lentiviral Particle (Silencing) targets angiopoietin-like 6, a hepatokine that regulates systemic energy expenditure and insulin sensitivity. Our platform offers both high-potency U6-driven and physiologically optimized miR30-based shRNA to study its metabolic effects. Every batch undergoes total quality control screening for functional titer, sequence accuracy, and sterility, ensuring that the tool provides a secure and high-performing solution for metabolic endocrinology.

Production Cell Line: HEK293T

Promoter: U6; CMV; EF1α; CAG; UBC

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Comprehensive sequencing and PCR analyses were performed to verify the accurate genomic sequence of all viral preparations.

Sterility Test: Confirmed sterile via rigorous microbial analysis; free of bacterial and fungal contamination.

Mycoplasma Test: Rigorous quality control testing has confirmed the absence of mycoplasma contamination in this viral preparation.

Other QC: Customized supplementary testing and in vitro/in vivo assessments are available to verify post-silencing gene expression and biological functionality, ensuring the viral preparations meet the specific potency requirements of your gene interference project.

Storage: Store at -80°C for long-term preservation. Immediate transfer upon delivery is required to prevent loss of viral activity.

Stability: Shelf life: 6–12 months at -80°C (extended stability up to 2 years). Post-thaw: Stable at 4°C for 2–3 weeks without significant degradation of functional titers.

Shipping Condition: Products are delivered on dry ice to maintain the cold chain. Upon arrival, please ensure the presence of dry ice and transfer the vials immediately to -80°C storage.

Handling Notes: Avoid repeated freeze-thaw cycles. Aliquot into low-protein-binding tubes immediately after receipt to maintain optimal activity. For safety and contamination control, all viral handling must be performed inside a biosafety cabinet.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: We ensure product integrity through rigorous QC, but we do not guarantee results in specific research contexts. Proper storage, handling, and total compliance with biosafety laws and safety protocols remain the sole responsibility of the user.

Target Profile

Gene Name: ANGPTL6

Full Name: Angiopoietin like 6

Gene Symbol: AGF; ARP5

Gene ID: 83854

RefSeq ID-1: NP_001308340.1

RefSeq ID-2: NM_001321411.2

Summary: ANGPTL6 encodes a secreted protein predicted to bind signaling receptors and regulate angiogenesis, blood coagulation, and cell differentiation. It is present in extracellular matrix compartments and exosomes. ANGPTL6 has been proposed as a biomarker of gestational diabetes and may play a compensatory role in obesity-related metabolic stress.

LipoKnoxa™ Human ANGPTL6 shRNA Lentiviral Particle (Silencing)

Product Overview

Specification

Target Profile

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