AdipoUpX™ Human SLC16A1 Lentiviral Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human SLC16A1 Lentiviral Particle (Overexpression) is a ready-to-use, high-titer vector particle professionally engineered for the long-lasting, stable overexpression of the human SLC16A1 gene. As the primary transporter for monocarboxylates like lactate and pyruvate, it is a vital tool for studying metabolic flexibility and fuel switching in adipocytes. Every batch undergoes rigorous quality control, including titer, sterility, and mycoplasma testing, to ensure experimental reproducibility and safety. Our modular vector system offers high flexibility for the customization of cell-specific promoters and reporter genes.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: PCR analysis was performed to verify the complete genomic sequence of all viral vector preparations.

Sterility Test: This product was certified sterile following successful microbial growth analysis.

Mycoplasma Test: The production quality control confirmed the absence of any mycoplasmal agents.

Other QC: This comprehensive process includes customized supplementary testing alongside in vitro and in vivo transduction assessments to elucidate transgene expression and functionality.

Storage: To maintain product integrity, immediate transfer of the vector to a -80 °C is essential following its receipt.

Stability: Continuous storage at -80°C ensures excellent long-term stability for 6-12 months. Once thawed, the product's working solution should be refrigerated at 4°C and used within 2-3 weeks.

Shipping Condition: Our lentivirus viral products are shipped using dry ice.

Handling Notes: Ensure all operations are performed within a biosafety cabinet; upon receiving the vector, immediately aliquot it into low-protein-binding tubes and store according to specified conditions, thus avoiding the titer loss caused by sensitivity to temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application, despite our company's commitment to product quality and the rigorous internal QC inspections all products have undergone. Ultimate responsibility remains with the user for all operational processes, including storage, handling, and compliance with safety and biosafety protocols.

Target Profile

Gene Name: SLC16A1

Full Name: Solute carrier family 16 member 1

Gene Symbol: MCT; HHF7; MCT1; MCT1D

Gene ID: 6566

RefSeq ID-1: NP_001159968.1

RefSeq ID-2: NM_001166496.2

Summary: The SLC16A1 gene encodes monocarboxylate transporter 1 (MCT1), a proton-coupled protein responsible for the rapid movement of lactate and pyruvate across the plasma membrane. This transport is vital for maintaining metabolic homeostasis in tissues with high glycolytic rates. Clinically, mutations in this gene are linked to erythrocyte lactate transporter deficiency, reflecting its indispensable role in cellular energy substrate exchange.

AdipoUpX™ Human SLC16A1 Lentiviral Particle (Overexpression)

Product Overview

Specification

Target Profile

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