AdipoUpX™ Human RAB23 MSCV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human RAB23 MSCV Particle (Overexpression) is a high-performance retroviral particle designed for stable expression of the human RAB23 gene. RAB23 regulates intracellular vesicle trafficking and has been linked to developmental and metabolic processes influencing adiposity. The MSCV system enables robust gene integration in hematopoietic stem cells, stem cells, and diverse mammalian cell lines. Comprehensive quality control, including viral titer analysis and sterility and mycoplasma testing, ensures consistent experimental outcomes.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Final QC confirmed the correct molecular size and integrity of the insert through specific PCR amplification.

Sterility Test: No microbial contamination was detected in any product.

Mycoplasma Test: No mycoplasma presence was detected in this final viral preparation upon comprehensive testing.

Other QC: Our service scope includes both customized supplementary testing and comprehensive in vitro/in vivo transduction assessments.

Storage: The necessity of immediate transfer to -80 °C storage following receipt is crucial for upholding the product's integrity.

Stability: Biological activity remains intact for 6-12 months when stored at -80°C. Once removed from the freezer, the diluted working material is stable for up to 2-3 weeks at 4°C.

Shipping Condition: Our MSCV retroviral products are shipped using dry ice.

Handling Notes: Store the vector according to specified conditions and aliquot it immediately upon receipt into low-protein-binding tubes, which is necessary to maintain titer because viral particles are highly sensitive to both temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Throughout all operational processes, users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements. Although our company commits to product quality via rigorous internal QC inspections, the complexity of experimental conditions means we cannot guarantee product performance or experimental results in any specific application.

Target Profile

Gene Name: RAB23

Full Name: RAB23, member RAS oncogene family

Gene Symbol: HSPC137

Gene ID: 51715

RefSeq ID-1: NP_001265595.1

RefSeq ID-2: NM_001278666.2

Summary: RAB23 is a small GTPase involved in intracellular membrane trafficking and cellular signaling. It is particularly important in development as an antagonist to the Sonic Hedgehog signaling pathway. Mutations in this gene can lead to Carpenter syndrome, which involves physical abnormalities and an increased risk of obesity, highlighting its role in coordinating developmental growth and metabolic health.

AdipoUpX™ Human RAB23 MSCV Particle (Overexpression)

Product Overview

Specification

Target Profile

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