AdipoUpX™ Human PLIN2 Lentiviral Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human PLIN2 Lentiviral Particle (Overexpression) is professionally engineered for the long-lasting, stable overexpression of the human PLIN2 (Adipophilin) gene. It is a reliable asset for studying the formation of small lipid droplets and the regulation of lipid storage in non-adipose tissues. This stable integration tool allows for systematic investigation into the molecular triggers of hepatic steatosis. The product is high-titer and ready-to-use, and all particles pass rigorous internal quality control validation (titer, sterility, and mycoplasma) to ensure the highest experimental standards.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: PCR analysis was performed to verify the complete genomic sequence of all viral vector preparations.

Sterility Test: This product was certified sterile following successful microbial growth analysis.

Mycoplasma Test: The production quality control confirmed the absence of any mycoplasmal agents.

Other QC: This comprehensive process includes customized supplementary testing alongside in vitro and in vivo transduction assessments to elucidate transgene expression and functionality.

Storage: To maintain product integrity, immediate transfer of the vector to a -80 °C is essential following its receipt.

Stability: Continuous storage at -80°C ensures excellent long-term stability for 6-12 months. Once thawed, the product's working solution should be refrigerated at 4°C and used within 2-3 weeks.

Shipping Condition: Our lentivirus viral products are shipped using dry ice.

Handling Notes: Ensure all operations are performed within a biosafety cabinet; upon receiving the vector, immediately aliquot it into low-protein-binding tubes and store according to specified conditions, thus avoiding the titer loss caused by sensitivity to temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application, despite our company's commitment to product quality and the rigorous internal QC inspections all products have undergone. Ultimate responsibility remains with the user for all operational processes, including storage, handling, and compliance with safety and biosafety protocols.

Target Profile

Gene Name: PLIN2

Full Name: Perilipin 2

Gene Symbol: ADFP; ADRP

Gene ID: 123

RefSeq ID-1: NP_001113.2

RefSeq ID-2: NM_001122.3

Summary: The PLIN2 protein serves as a protective coating for intracellular lipid droplets. While once thought to be exclusive to fat cells, it is now recognized as a universal marker for lipid accumulation across many tissues, including the liver and mammary glands. It is essential for the orderly storage and mobilization of fats, preventing lipid-induced toxicity in non-adipose tissues.

AdipoUpX™ Human PLIN2 Lentiviral Particle (Overexpression)

Product Overview

Specification

Target Profile

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