AdipoUpX™ Human PPARD Lentiviral Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human PPARD Lentiviral Particle (Overexpression) is a ready-to-use, high-titer vector particle designed for the efficient and stable overexpression of the human PPARD gene. This nuclear receptor is a master regulator of fatty acid oxidation in skeletal muscle and adipose tissue. By integrating into the host genome, it allows for the establishment of reliable cell lines to study metabolic rate and "fat-burning" phenotypes. Every batch is validated through comprehensive quality control (titer, sterility, and mycoplasma testing) to ensure research safety and experimental reproducibility.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: PCR analysis was performed to verify the complete genomic sequence of all viral vector preparations.

Sterility Test: This product was certified sterile following successful microbial growth analysis.

Mycoplasma Test: The production quality control confirmed the absence of any mycoplasmal agents.

Other QC: This comprehensive process includes customized supplementary testing alongside in vitro and in vivo transduction assessments to elucidate transgene expression and functionality.

Storage: To maintain product integrity, immediate transfer of the vector to a -80 °C is essential following its receipt.

Stability: Continuous storage at -80°C ensures excellent long-term stability for 6-12 months. Once thawed, the product's working solution should be refrigerated at 4°C and used within 2-3 weeks.

Shipping Condition: Our lentivirus viral products are shipped using dry ice.

Handling Notes: Ensure all operations are performed within a biosafety cabinet; upon receiving the vector, immediately aliquot it into low-protein-binding tubes and store according to specified conditions, thus avoiding the titer loss caused by sensitivity to temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application, despite our company's commitment to product quality and the rigorous internal QC inspections all products have undergone. Ultimate responsibility remains with the user for all operational processes, including storage, handling, and compliance with safety and biosafety protocols.

Target Profile

Gene Name: PPARD

Full Name: Peroxisome proliferator activated receptor delta

Gene Symbol: FAAR; NUC1; NUCI; NR1C2; NUCII; PPARB

Gene ID: 5467

RefSeq ID-1: NP_001165289.1

RefSeq ID-2: NM_001171818.2

Summary: PPARD encodes a nuclear receptor of the PPAR family that regulates transcriptional programs involved in lipid metabolism and energy utilization. The protein influences fatty acid oxidation, cellular differentiation, and metabolic flexibility. Experimental models suggest PPARD activity impacts body composition and susceptibility to metabolic disease.

AdipoUpX™ Human PPARD Lentiviral Particle (Overexpression)

Product Overview

Specification

Target Profile

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