AdipoUpX™ Human MYT1L Lentiviral Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human MYT1L Lentiviral Particle (Overexpression) is professionally engineered for the efficient and long-lasting overexpression of the human MYT1L gene. This transcription factor is essential for neuronal identity and has been linked to severe hyperphagic obesity. Genome integration enables the establishment of stable cell lines for investigating neurodevelopmental metabolic triggers. All viral particle products undergo comprehensive quality control to ensure efficacy and the highest standards for neuro-metabolic research.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: PCR analysis was performed to verify the complete genomic sequence of all viral vector preparations.

Sterility Test: This product was certified sterile following successful microbial growth analysis.

Mycoplasma Test: The production quality control confirmed the absence of any mycoplasmal agents.

Other QC: This comprehensive process includes customized supplementary testing alongside in vitro and in vivo transduction assessments to elucidate transgene expression and functionality.

Storage: To maintain product integrity, immediate transfer of the vector to a -80 °C is essential following its receipt.

Stability: Continuous storage at -80°C ensures excellent long-term stability for 6-12 months. Once thawed, the product's working solution should be refrigerated at 4°C and used within 2-3 weeks.

Shipping Condition: Our lentivirus viral products are shipped using dry ice.

Handling Notes: Ensure all operations are performed within a biosafety cabinet; upon receiving the vector, immediately aliquot it into low-protein-binding tubes and store according to specified conditions, thus avoiding the titer loss caused by sensitivity to temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application, despite our company's commitment to product quality and the rigorous internal QC inspections all products have undergone. Ultimate responsibility remains with the user for all operational processes, including storage, handling, and compliance with safety and biosafety protocols.

Target Profile

Gene Name: MYT1L

Full Name: Myelin transcription factor 1 like

Gene Symbol: NZF1; MRD39; myT1-L; ZC2H2C2; ZC2HC4B

Gene ID: 23040

RefSeq ID-1: NP_001289981.1

RefSeq ID-2: NM_001303052.2

Summary: MYT1L encodes a neuronal-specific zinc finger transcription factor involved in central nervous system development. Together with other transcription factors, MYT1L can reprogram fibroblasts into functional neurons capable of generating action potentials. Mutations in this gene have been linked to autosomal dominant cognitive disabilities and autism spectrum disorder. Multiple transcript variants exist due to alternative splicing.

AdipoUpX™ Human MYT1L Lentiviral Particle (Overexpression)

Product Overview

Specification

Target Profile

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