AdipoUpX™ Human GHSR Lentiviral Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human GHSR Lentiviral Particle (Overexpression) is professionally engineered for the long-lasting, stable overexpression of the human GHSR gene. As the receptor for ghrelin, its stable expression in cell models allows for systematic investigation into appetite stimulation and growth hormone secretion mechanisms. The product is ready-to-use and high-titer, with safety and efficacy guaranteed by rigorous internal QC, including titer and purity validation. Clients can freely select reporter genes to monitor receptor activation and its impact on downstream signaling pathways.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: PCR analysis was performed to verify the complete genomic sequence of all viral vector preparations.

Sterility Test: This product was certified sterile following successful microbial growth analysis.

Mycoplasma Test: The production quality control confirmed the absence of any mycoplasmal agents.

Other QC: This comprehensive process includes customized supplementary testing alongside in vitro and in vivo transduction assessments to elucidate transgene expression and functionality.

Storage: To maintain product integrity, immediate transfer of the vector to a -80 °C is essential following its receipt.

Stability: Continuous storage at -80°C ensures excellent long-term stability for 6-12 months. Once thawed, the product's working solution should be refrigerated at 4°C and used within 2-3 weeks.

Shipping Condition: Our lentivirus viral products are shipped using dry ice.

Handling Notes: Ensure all operations are performed within a biosafety cabinet; upon receiving the vector, immediately aliquot it into low-protein-binding tubes and store according to specified conditions, thus avoiding the titer loss caused by sensitivity to temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application, despite our company's commitment to product quality and the rigorous internal QC inspections all products have undergone. Ultimate responsibility remains with the user for all operational processes, including storage, handling, and compliance with safety and biosafety protocols.

Target Profile

Gene Name: GHSR

Full Name: Growth hormone secretagogue receptor

Gene Symbol: GHDP; GHS-R1a; GHSR-1a

Gene ID: 2693

RefSeq ID-1: NP_004113.1

RefSeq ID-2: NM_004122.2

Summary: GHSR encodes a ghrelin-responsive G protein–coupled receptor that participates in neuroendocrine regulation of appetite and growth hormone secretion. The functional receptor isoform mediates ghrelin signaling that promotes food intake and energy storage, while alternative isoforms may modulate receptor activity. GHSR signaling is therefore central to body weight regulation.

AdipoUpX™ Human GHSR Lentiviral Particle (Overexpression)

Product Overview

Specification

Target Profile

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