AdipoUpX™ Human OPA1 MMLV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human OPA1 MMLV Particle (Overexpression) is a powerful gene delivery tool designed for the stable overexpression of the human OPA1 gene. It is central to mitochondrial inner membrane fusion and cristae maintenance, playing a protective role against metabolic stress. Because the MMLV particle integrates into the host cell genome, it is an ideal tool for establishing permanent cell lines to study mitochondrial dynamics. Comprehensive quality control ensures the safety and efficacy of all viral products, providing a reliable asset for bioenergetics research.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Complete verification of the vector genome's integrity was achieved for every viral preparation using the PCR method.

Sterility Test: The final viral preparation was confirmed sterile after testing.

Mycoplasma Test: Mycoplasma contamination testing met all release specifications for all product lots.

Other QC: We also provide additional testing services tailored to specific project requirements. Additionally, we conduct customized assessments to analyze the expression levels and biological functions of genetically modified organisms.

Storage: The product must be immediately transferred to -80 °C storage upon its arrival.

Stability: For long-term storage, the product guarantees excellent stability for 6-12 months at -80°C. After thawing, refrigeration at 4°C allows use of the working solution for 2-3 weeks.

Shipping Condition: Our MMLV retroviral products are shipped using dry ice.

Handling Notes: Due to their high sensitivity to temperature fluctuations and damaging freeze-thaw cycles, viral particles should be aliquoted into low-protein-binding tubes immediately upon receipt to maintain titer and product integrity. This procedure must be conducted within a biosafety cabinet.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: All products have undergone rigorous internal QC inspections as part of our company's commitment to product quality. However, due to the diversity and complexity of experimental conditions, users bear ultimate responsibility for product storage, handling, and compliance with all safety and biosafety protocols, and we offer no guarantee of product performance or experimental results in any specific application.

Target Profile

Gene Name: OPA1

Full Name: OPA1 mitochondrial dynamin like GTPase

Gene Symbol: NPG; NTG; MGM1; BERHS; largeG; MTDPS14

Gene ID: 4976

RefSeq ID-1: NP_056375.2

RefSeq ID-2: NM_015560.3

Summary: OPA1 encodes a dynamin-like GTPase in the inner mitochondrial membrane, essential for mitochondrial fusion, energy production, and cytochrome c sequestration. By maintaining mitochondrial efficiency, OPA1 indirectly influences energy metabolism, and its dysregulation may contribute to metabolic imbalance relevant to obesity.

AdipoUpX™ Human OPA1 MMLV Particle (Overexpression)

Product Overview

Specification

Target Profile

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