AdipoUpX™ Human EIF2S3 MSCV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human EIF2S3 MSCV Particle (Overexpression) is a high-titer retroviral system designed for the stable expression of eukaryotic translation initiation factor 2 subunit gamma. This product allows researchers to investigate the link between protein synthesis initiation and metabolic syndrome. The MSCV system ensures stable, high-level gene integration within hematopoietic stem cells, stem cells, and various mammalian cell lines. Rigorous testing for titer, sterility, and mycoplasma is performed on every batch to provide a reliable tool for studying the metabolic consequences of translational regulation.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Final QC confirmed the correct molecular size and integrity of the insert through specific PCR amplification.

Sterility Test: No microbial contamination was detected in any product.

Mycoplasma Test: No mycoplasma presence was detected in this final viral preparation upon comprehensive testing.

Other QC: Our service scope includes both customized supplementary testing and comprehensive in vitro/in vivo transduction assessments.

Storage: The necessity of immediate transfer to -80 °C storage following receipt is crucial for upholding the product's integrity.

Stability: Biological activity remains intact for 6-12 months when stored at -80°C. Once removed from the freezer, the diluted working material is stable for up to 2-3 weeks at 4°C.

Shipping Condition: Our MSCV retroviral products are shipped using dry ice.

Handling Notes: Store the vector according to specified conditions and aliquot it immediately upon receipt into low-protein-binding tubes, which is necessary to maintain titer because viral particles are highly sensitive to both temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Throughout all operational processes, users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements. Although our company commits to product quality via rigorous internal QC inspections, the complexity of experimental conditions means we cannot guarantee product performance or experimental results in any specific application.

Target Profile

Gene Name: EIF2S3

Full Name: Eukaryotic translation initiation factor 2 subunit gamma

Gene Symbol: EIF2; EIF2G; MEHMO; eIF2gX; MRXSBRK; eIF-2gA; EIF2gamma

Gene ID: 1968

RefSeq ID-1: NP_001406.1

RefSeq ID-2: NM_001415.4

Summary: EIF2S3 encodes the largest subunit of a heterotrimeric GTP-binding protein critical for initiating protein synthesis. It mediates the recruitment of methionyl-tRNA(i) to the 40S ribosomal subunit, a key step in translation initiation.

AdipoUpX™ Human EIF2S3 MSCV Particle (Overexpression)

Product Overview

Specification

Target Profile

Related Products