AdipoUpX™ Human CCKAR Lentiviral Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human CCKAR Lentiviral Particle (Overexpression) is professionally engineered for the long-lasting, stable overexpression of the human CCKAR gene. As the primary receptor for cholecystokinin in the gut and brain, its stable integration into host cells allows for systematic investigation into peripheral satiety signaling and gallbladder motility. The product is ready-to-use and high-titer, with safety and data integrity guaranteed by rigorous internal QC, including sterility and mycoplasma detection. Clients can flexibly select reporter genes to meet their unique experimental needs.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: PCR analysis was performed to verify the complete genomic sequence of all viral vector preparations.

Sterility Test: This product was certified sterile following successful microbial growth analysis.

Mycoplasma Test: The production quality control confirmed the absence of any mycoplasmal agents.

Other QC: This comprehensive process includes customized supplementary testing alongside in vitro and in vivo transduction assessments to elucidate transgene expression and functionality.

Storage: To maintain product integrity, immediate transfer of the vector to a -80 °C is essential following its receipt.

Stability: Continuous storage at -80°C ensures excellent long-term stability for 6-12 months. Once thawed, the product's working solution should be refrigerated at 4°C and used within 2-3 weeks.

Shipping Condition: Our lentivirus viral products are shipped using dry ice.

Handling Notes: Ensure all operations are performed within a biosafety cabinet; upon receiving the vector, immediately aliquot it into low-protein-binding tubes and store according to specified conditions, thus avoiding the titer loss caused by sensitivity to temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application, despite our company's commitment to product quality and the rigorous internal QC inspections all products have undergone. Ultimate responsibility remains with the user for all operational processes, including storage, handling, and compliance with safety and biosafety protocols.

Target Profile

Gene Name: CCKAR

Full Name: Cholecystokinin A receptor

Gene Symbol: CCK-A; CCK1R; CCKRA; CCK-1R; CCK1-R

Gene ID: 886

RefSeq ID-1: NP_000721.1

RefSeq ID-2: NM_000730.3

Summary: CCKAR encodes a G-protein-coupled receptor for cholecystokinin (CCK) peptides, mediating satiety signals in the central and peripheral nervous systems. It also regulates pancreatic enzyme secretion and smooth muscle contraction in the digestive tract. Genetic variants affecting CCKAR function can influence appetite, feeding behavior, and obesity susceptibility.

AdipoUpX™ Human CCKAR Lentiviral Particle (Overexpression)

Product Overview

Specification

Target Profile

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