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Human proinsulin (PI) ELISA kit (0.625-40 pmol/mL)
Cat. No.:
0126WXX-1584
Assay Type:
Quantitative sandwich ELISA
Target Species:
Human
Assay Target:
PI
Size:
Add to basket
Product Overview
Description:
Human proinsulin (PI) ELISA kit (0.625-40 pmol/mL) is an ELISA-based in vitro research tool designed specifically for the quantitative detection of PI in human samples with a range of 0.625-40 pmol/mL and a minimum detectable dose (sensitivity) of 0.31 pmol/mL. The kit is highly sensitive and easy to use.
Assay Principle:
The ELISA analytical biochemical technique is based on PI antibody-PI antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PI antigen targets in samples.
Background:
Proinsulin is the precursor molecule of insulin, synthesized in pancreatic β cells and subsequently processed into mature insulin and C-peptide. It plays a critical role in glucose homeostasis by serving as an essential intermediate in insulin biosynthesis and secretion. Under normal physiological conditions, proinsulin is efficiently converted to insulin; however, impaired processing or increased proinsulin secretion reflects β-cell dysfunction. Elevated circulating proinsulin levels are commonly observed in obesity and insulin resistance, making proinsulin a key indicator of metabolic stress and a contributing factor to the development of obesity-associated type 2 diabetes.
Synonyms:
INS; Pro-Insulin; Preproinsulin
Applications:
Human proinsulin (PI) ELISA kit (0.625-40 pmol/mL) is used to quantify PI in human samples, providing data to support research in a wide range of areas, including endocrinology, hormone metabolism, obesity, and others.
Research Area:
Endocrinology; Hormone metabolism; Obesity
Specification
Sample Type:
Human samples
Detection Range:
0.625-40 pmol/mL
Sensitivity:
0.31 pmol/mL
Cross-reactivity:
No significant cross-reactivity or interference was observed.
Storage:
Store at -20°C.


