Human plasminogen activator inhibitor-1 (PAI-1) ELISA kit (12.5-800 pg/mL)

Cat. No.: 0126WXX-1221

Assay Type: Quantitative sandwich ELISA

Target Species: Human

Assay Target: PAI-1

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Human plasminogen activator inhibitor-1 (PAI-1) ELISA kit (12.5-800 pg/mL)

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Product Overview

Description: Human plasminogen activator inhibitor-1 (PAI-1) ELISA kit (12.5-800 pg/mL, 4.9 pg/mL) is an ELISA-based in vitro research tool designed specifically for the quantitative detection of PAI-1 in human samples with a range of 12.5-800 pg/mL and a minimum detectable dose (sensitivity) of 4.9 pg/mL. The kit is highly sensitive and easy to use.

Assay Principle: The ELISA analytical biochemical technique is based on PAI-1 antibody-PAI-1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PAI-1 antigen targets in samples.

Background: As the primary physiological inhibitor of tissue-type plasminogen activator and urokinase-type plasminogen activator, PAI-1 exerts its effects by suppressing fibrinolysis and proteolysis. Its elevation is associated not only with thrombosis and fibrosis but also with obesity and insulin resistance.

Synonyms: SERPINE1; Endothelial plasminogen activator inhibitor

Applications: Human plasminogen activator inhibitor-1 (PAI-1) ELISA kit (12.5-800 pg/mL, 4.9 pg/mL) is used to quantify PAI-1 in serum, plasma, tissue homogenates, and cell lysates, cell culture supernatants, and other biological fluids of human, providing data to support research in a wide range of areas, including metabolism, fibrosis, thrombosis, obesity, etc.

Research Area: Metabolism; Fibrosis; Thrombosis; Obesity

Specification

Sample Type: Serum; Plasma; Tissue homogenates; Cell lysates; Cell culture supernatants; Other biological fluids

Detection Range: 12.5-800 pg/mL

Sensitivity: 4.9 pg/mL

Precision (Intra-assay): CV<10%

Precision (Inter-assay): CV<12%

Cross-reactivity: No significant cross-reactivity or interference was observed.

Storage: Store at 4°C (TMB substrate, wash buffer, stop solution) and -20°C (others).

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