Human cathepsin S (CTSS) ELISA kit (78-5000 pg/mL, 34 pg/mL)

Cat. No.: OB0625WXX-527

Assay Type: Quantitative sandwich ELISA

Target Species: Human

Assay Target: CTSS

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Human cathepsin S (CTSS) ELISA kit (78-5000 pg/mL, 34 pg/mL)

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Product Overview

Description: Human cathepsin S (CTSS) ELISA kit (78-5000 pg/mL, 34 pg/mL) is an ELISA-based in vitro research tool designed specifically for the quantitative detection of CTSS in human with a range of 78-5000 pg/mL and a specificity of 34 pg/mL.

Assay Principle: The microtiter plate provided in this kit is pre-coated with an antibody specific for CTSS. Standards or samples are then added to the appropriate microtiter plate wells along with a biotin-conjugated antibody preparation specific for CTSS, and avidin conjugated to horseradish peroxidase (HRP) is then added to each microtiter plate well and incubated. TMB substrate solution is then added to each well. Only wells containing CTSS, biotin-conjugated antibody, and enzyme-conjugated avidin will show a color change. The enzyme-substrate reaction is terminated by the addition of sulfuric acid solution, and the color change is measured spectrophotometrically at 450 nm ± 2 nm. The concentration of CTSS in the sample is then determined by comparing the OD of the sample to a standard curve.

Background: CTSS is an important member of the cysteine protease family. As a potent mammalian elastase, it can degrade various extracellular components, including fibronectin, laminin, elastin, and collagen. CTSS is abnormally expressed in various disease states, such as obesity and atherosclerosis, which makes it a biomarker and a potential therapeutic target. Studies have found that CTSS inhibitors may be a possible strategy for treating obesity.

Synonyms: CTS-S; EC 3.4.22.27

EC NO.: 3.4.22.27

Applications: Human cathepsin S (CTSS) ELISA kit (78-5000 pg/mL, 34 pg/mL) is used to quantify CTSS in biological samples of humans, providing data to support a wide range of studies.

Research Area: Obesity research; Immune response; Signaling pathway; Protein degradation

Specification

Sample Type: Biological samples

Detection Range: 78-5000 pg/mL

Sensitivity: 34 pg/mL

Cross-reactivity: No significant cross-reactivity or interference was observed.

Storage: Store at 2-8°C.

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