AdipoUpX™ Human UCP2 Lentiviral Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human UCP2 Lentiviral Particle (Overexpression) is professionally engineered for the long-lasting, stable overexpression of the human UCP2 gene. This mitochondrial uncoupling protein is a key target for investigating cellular energy efficiency and insulin secretion mechanisms. This ready-to-use, high-titer product allows for the systematic investigation of oxidative stress in metabolic dysfunction. Every batch undergoes rigorous internal quality control, and the modular design supports high flexibility for the customization of markers and promoters.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: PCR analysis was performed to verify the complete genomic sequence of all viral vector preparations.

Sterility Test: This product was certified sterile following successful microbial growth analysis.

Mycoplasma Test: The production quality control confirmed the absence of any mycoplasmal agents.

Other QC: This comprehensive process includes customized supplementary testing alongside in vitro and in vivo transduction assessments to elucidate transgene expression and functionality.

Storage: To maintain product integrity, immediate transfer of the vector to a -80 °C is essential following its receipt.

Stability: Continuous storage at -80°C ensures excellent long-term stability for 6-12 months. Once thawed, the product's working solution should be refrigerated at 4°C and used within 2-3 weeks.

Shipping Condition: Our lentivirus viral products are shipped using dry ice.

Handling Notes: Ensure all operations are performed within a biosafety cabinet; upon receiving the vector, immediately aliquot it into low-protein-binding tubes and store according to specified conditions, thus avoiding the titer loss caused by sensitivity to temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application, despite our company's commitment to product quality and the rigorous internal QC inspections all products have undergone. Ultimate responsibility remains with the user for all operational processes, including storage, handling, and compliance with safety and biosafety protocols.

Target Profile

Gene Name: UCP2

Full Name: Uncoupling protein 2

Gene Symbol: UCPH; BMIQ4; SLC25A8

Gene ID: 7351

RefSeq ID-1: NP_001368872.1

RefSeq ID-2: NM_001381943.1

Summary: UCP2 codes for a member of the mitochondrial anion carrier protein family that mediates the "proton leak". This process effectively uncouples oxidative phosphorylation from ATP synthesis, releasing energy as heat. Expressed broadly across tissues, with peak levels in skeletal muscle, UCP2 is theorized to play a role in nonshivering thermogenesis and in protecting cells against oxidative stress. Its function has significant implications for obesity and diabetes susceptibility, positioning it as a key regulator of metabolic efficiency and cellular defense.

AdipoUpX™ Human UCP2 Lentiviral Particle (Overexpression)

Product Overview

Specification

Target Profile

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