AdipoUpX™ Human FABP5 Lentiviral Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human FABP5 Lentiviral Particle (Overexpression) is a powerful gene delivery tool specifically designed for the stable overexpression of the human FABP5 gene. This fatty acid chaperone is critical for researching the transport of lipids to the nucleus for PPAR activation and its link to skin and adipose health. All particles undergo rigorous quality control screening to ensure experimental reliability. Our customizable platform supports the flexible inclusion of fluorescent tags and reporter genes for real-time visualization of lipid trafficking.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: PCR analysis was performed to verify the complete genomic sequence of all viral vector preparations.

Sterility Test: This product was certified sterile following successful microbial growth analysis.

Mycoplasma Test: The production quality control confirmed the absence of any mycoplasmal agents.

Other QC: This comprehensive process includes customized supplementary testing alongside in vitro and in vivo transduction assessments to elucidate transgene expression and functionality.

Storage: To maintain product integrity, immediate transfer of the vector to a -80 °C is essential following its receipt.

Stability: Continuous storage at -80°C ensures excellent long-term stability for 6-12 months. Once thawed, the product's working solution should be refrigerated at 4°C and used within 2-3 weeks.

Shipping Condition: Our lentivirus viral products are shipped using dry ice.

Handling Notes: Ensure all operations are performed within a biosafety cabinet; upon receiving the vector, immediately aliquot it into low-protein-binding tubes and store according to specified conditions, thus avoiding the titer loss caused by sensitivity to temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application, despite our company's commitment to product quality and the rigorous internal QC inspections all products have undergone. Ultimate responsibility remains with the user for all operational processes, including storage, handling, and compliance with safety and biosafety protocols.

Target Profile

Gene Name: FABP5

Full Name: Fatty acid binding protein 5

Gene Symbol: EFABP; KFABP; E-FABP; PAFABP; PA-FABP

Gene ID: 2171

RefSeq ID-1: NP_001435.1

RefSeq ID-2: NM_001444.3

Summary: FABP5 encodes a fatty acid–binding protein originally identified in epidermal cells and upregulated in psoriasis. Like other FABPs, it binds long-chain fatty acids and hydrophobic ligands, facilitating lipid uptake, intracellular transport, and metabolism. FABP5 is increasingly recognized as a regulator of lipid signaling pathways in adipocytes and macrophages, linking it to obesity, insulin resistance, and type 2 diabetes. Numerous pseudogenes related to FABP5 are present in the human genome.

AdipoUpX™ Human FABP5 Lentiviral Particle (Overexpression)

Product Overview

Specification

Target Profile

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