AdipoUpX™ Human LIPE Lentiviral Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human LIPE Lentiviral Particle (Overexpression) is a powerful gene delivery tool specifically designed for the stable overexpression of the human LIPE (HSL) gene. Hormone-sensitive lipase is essential for researching the mobilization of fatty acids from adipose stores. Genome integration enables the long-term validation of HSL activity in insulin-resistant environments. All viral products undergo rigorous internal quality control to ensure reliability, and clients can flexibly customize functional components to suit their specific metabolic research models.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: PCR analysis was performed to verify the complete genomic sequence of all viral vector preparations.

Sterility Test: This product was certified sterile following successful microbial growth analysis.

Mycoplasma Test: The production quality control confirmed the absence of any mycoplasmal agents.

Other QC: This comprehensive process includes customized supplementary testing alongside in vitro and in vivo transduction assessments to elucidate transgene expression and functionality.

Storage: To maintain product integrity, immediate transfer of the vector to a -80 °C is essential following its receipt.

Stability: Continuous storage at -80°C ensures excellent long-term stability for 6-12 months. Once thawed, the product's working solution should be refrigerated at 4°C and used within 2-3 weeks.

Shipping Condition: Our lentivirus viral products are shipped using dry ice.

Handling Notes: Ensure all operations are performed within a biosafety cabinet; upon receiving the vector, immediately aliquot it into low-protein-binding tubes and store according to specified conditions, thus avoiding the titer loss caused by sensitivity to temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application, despite our company's commitment to product quality and the rigorous internal QC inspections all products have undergone. Ultimate responsibility remains with the user for all operational processes, including storage, handling, and compliance with safety and biosafety protocols.

Target Profile

Gene Name: LIPE

Full Name: Lipase E, hormone sensitive type

Gene Symbol: HSL; LHS; REH; AOMS4; FPLD6

Gene ID: 3991

RefSeq ID-1: NP_001403032.1

RefSeq ID-2: NM_001416103.1

Summary: LIPE encodes hormone-sensitive lipase with long and short isoforms generated through alternative translational start sites. The long isoform is expressed in steroidogenic tissues, such as the testis, where it hydrolyzes cholesteryl esters for steroid hormone synthesis. The short isoform, expressed in adipose tissue, mobilizes stored triglycerides by converting them into free fatty acids, thereby playing a key role in lipid metabolism.

AdipoUpX™ Human LIPE Lentiviral Particle (Overexpression)

Product Overview

Specification

Target Profile

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