AdipoUpX™ Human FASN Lentiviral Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human FASN Lentiviral Particle (Overexpression) is professionally engineered for the long-lasting, stable overexpression of the human FASN gene. Fatty acid synthase is the central enzyme for de novo lipogenesis; this stable integration tool allows for systematic research into the energetic shifts that favor fat storage. The product is high-titer and ready-to-use, with every batch passing rigorous internal quality control, including titer and purity validation. Our customizable platform allows for the flexible selection of reporter genes for precise tracking.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: PCR analysis was performed to verify the complete genomic sequence of all viral vector preparations.

Sterility Test: This product was certified sterile following successful microbial growth analysis.

Mycoplasma Test: The production quality control confirmed the absence of any mycoplasmal agents.

Other QC: This comprehensive process includes customized supplementary testing alongside in vitro and in vivo transduction assessments to elucidate transgene expression and functionality.

Storage: To maintain product integrity, immediate transfer of the vector to a -80 °C is essential following its receipt.

Stability: Continuous storage at -80°C ensures excellent long-term stability for 6-12 months. Once thawed, the product's working solution should be refrigerated at 4°C and used within 2-3 weeks.

Shipping Condition: Our lentivirus viral products are shipped using dry ice.

Handling Notes: Ensure all operations are performed within a biosafety cabinet; upon receiving the vector, immediately aliquot it into low-protein-binding tubes and store according to specified conditions, thus avoiding the titer loss caused by sensitivity to temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application, despite our company's commitment to product quality and the rigorous internal QC inspections all products have undergone. Ultimate responsibility remains with the user for all operational processes, including storage, handling, and compliance with safety and biosafety protocols.

Target Profile

Gene Name: FASN

Full Name: Fatty acid synthase

Gene Symbol: FAS; OA-519; SDR27X1

Gene ID: 2194

RefSeq ID-1: NP_004095.4

RefSeq ID-2: NM_004104.4

Summary: FASN is the primary multi-enzyme system responsible for de novo lipogenesis. Its main task is the synthesis of palmitate from acetyl-CoA and malonyl-CoA. In a metabolic context, FASN is the machinery that converts excess energy into long-chain saturated fatty acids. While critical for normal energy storage, its dysregulation is associated with metabolic syndrome, and its fusion with other receptors has been observed in specific cancer lineages.

AdipoUpX™ Human FASN Lentiviral Particle (Overexpression)

Product Overview

Specification

Target Profile

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