AdipoUpX™ Human PRMT7 Lentiviral Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human PRMT7 Lentiviral Particle (Overexpression) is a ready-to-use, high-titer vector particle designed for the stable overexpression of the human PRMT7 gene. As a protein arginine methyltransferase, it is critical for researching the epigenetic regulation of muscle development and adipogenesis. The lentivirus characteristics ensure the target gene integrates into the host cell genome, establishing reliable stable cell lines for longitudinal study. Our vector system features a modular design, offering high flexibility for customization through various markers and promoters.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: PCR analysis was performed to verify the complete genomic sequence of all viral vector preparations.

Sterility Test: This product was certified sterile following successful microbial growth analysis.

Mycoplasma Test: The production quality control confirmed the absence of any mycoplasmal agents.

Other QC: This comprehensive process includes customized supplementary testing alongside in vitro and in vivo transduction assessments to elucidate transgene expression and functionality.

Storage: To maintain product integrity, immediate transfer of the vector to a -80 °C is essential following its receipt.

Stability: Continuous storage at -80°C ensures excellent long-term stability for 6-12 months. Once thawed, the product's working solution should be refrigerated at 4°C and used within 2-3 weeks.

Shipping Condition: Our lentivirus viral products are shipped using dry ice.

Handling Notes: Ensure all operations are performed within a biosafety cabinet; upon receiving the vector, immediately aliquot it into low-protein-binding tubes and store according to specified conditions, thus avoiding the titer loss caused by sensitivity to temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application, despite our company's commitment to product quality and the rigorous internal QC inspections all products have undergone. Ultimate responsibility remains with the user for all operational processes, including storage, handling, and compliance with safety and biosafety protocols.

Target Profile

Gene Name: PRMT7

Full Name: Protein arginine methyltransferase 7

Gene Symbol: SBIDDS

Gene ID: 54496

RefSeq ID-1: NP_001171753.1

RefSeq ID-2: NM_001184824.4

Summary: PRMT7 encodes a member of the protein arginine N-methyltransferase family. The enzyme transfers methyl groups to arginine residues on histones and other proteins, generating monomethylarginines. It plays roles in neuronal differentiation, male germline imprinting, small nuclear ribonucleoprotein biogenesis, and regulation of Wnt signaling. Mutations in PRMT7 are associated with syndromes involving intellectual disability, short stature, and other features. Additionally, the protein may enhance breast cancer cell invasion and metastasis.

AdipoUpX™ Human PRMT7 Lentiviral Particle (Overexpression)

Product Overview

Specification

Target Profile

Related Products