AdipoUpX™ Human PHF21A MMLV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human PHF21A MMLV Particle (Overexpression) is a stable integration tool for the specific and efficient overexpression of the human PHF21A gene. Associated with neurodevelopmental disorders and metabolic dysfunction, it serves as a critical transcription co-repressor. This MMLV product allows for the longitudinal investigation of its role in epigenetic regulation within dividing host cells. Product quality is ensured by rigorous purification and comprehensive QC screening, including titer and mycoplasma testing, to guarantee the highest experimental standards.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Complete verification of the vector genome's integrity was achieved for every viral preparation using the PCR method.

Sterility Test: The final viral preparation was confirmed sterile after testing.

Mycoplasma Test: Mycoplasma contamination testing met all release specifications for all product lots.

Other QC: We also provide additional testing services tailored to specific project requirements. Additionally, we conduct customized assessments to analyze the expression levels and biological functions of genetically modified organisms.

Storage: The product must be immediately transferred to -80 °C storage upon its arrival.

Stability: For long-term storage, the product guarantees excellent stability for 6-12 months at -80°C. After thawing, refrigeration at 4°C allows use of the working solution for 2-3 weeks.

Shipping Condition: Our MMLV retroviral products are shipped using dry ice.

Handling Notes: Due to their high sensitivity to temperature fluctuations and damaging freeze-thaw cycles, viral particles should be aliquoted into low-protein-binding tubes immediately upon receipt to maintain titer and product integrity. This procedure must be conducted within a biosafety cabinet.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: All products have undergone rigorous internal QC inspections as part of our company's commitment to product quality. However, due to the diversity and complexity of experimental conditions, users bear ultimate responsibility for product storage, handling, and compliance with all safety and biosafety protocols, and we offer no guarantee of product performance or experimental results in any specific application.

Target Profile

Gene Name: PHF21A

Full Name: PHD finger protein 21A

Gene Symbol: BHC80; NEDMS; BM-006; IDDBCS

Gene ID: 51317

RefSeq ID-1: NP_001095272.1

RefSeq ID-2: NM_001101802.3

Summary: PHF21A produces a component of the BRAF35-HDAC complex. It acts as a transcriptional repressor, specifically silencing genes that are meant to be expressed only in neurons. By preventing the expression of these genes in non-neural tissues, it maintains the precise identity of different cell types throughout the body.

AdipoUpX™ Human PHF21A MMLV Particle (Overexpression)

Product Overview

Specification

Target Profile

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