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AdipoUpX™ Human LPIN2 Lentiviral Particle (Overexpression)
Cat. No.:
V1225XX536
Species:
Human
Target Gene:
LPIN2
Vector System:
Lentiviral
Modulation Type:
Overexpression
SPECIFIC INQUIRY
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Product Overview
Description:
AdipoUpX™ Human LPIN2 Lentiviral Particle (Overexpression) is a ready-to-use, high-titer vector particle designed for the stable overexpression of the human LPIN2 gene. Lipin-2 acts as both a phosphatidate phosphatase and a transcriptional coactivator, making it a powerful tool for researching glycerolipid synthesis and inflammatory regulation. To ensure the repeatability of your data, every batch undergoes rigorous quality control, including titer and sterility testing. Our modular vector design offers researchers the ability to flexibly select markers for high-fidelity tracking.
Production Cell Line:
HEK293T
Promoter:
Ubi; CMV; EF1a; Others
Product Availability:
Produced Upon Order
Specification
Titer Test:
qPCR
Insert Verification:
PCR analysis was performed to verify the complete genomic sequence of all viral vector preparations.
Sterility Test:
This product was certified sterile following successful microbial growth analysis.
Mycoplasma Test:
The production quality control confirmed the absence of any mycoplasmal agents.
Other QC:
This comprehensive process includes customized supplementary testing alongside in vitro and in vivo transduction assessments to elucidate transgene expression and functionality.
Storage:
To maintain product integrity, immediate transfer of the vector to a -80 °C is essential following its receipt.
Stability:
Continuous storage at -80°C ensures excellent long-term stability for 6-12 months. Once thawed, the product's working solution should be refrigerated at 4°C and used within 2-3 weeks.
Shipping Condition:
Our lentivirus viral products are shipped using dry ice.
Handling Notes:
Ensure all operations are performed within a biosafety cabinet; upon receiving the vector, immediately aliquot it into low-protein-binding tubes and store according to specified conditions, thus avoiding the titer loss caused by sensitivity to temperature fluctuations and freeze-thaw cycles.
Intended Use:
This product is intended for research use only and is not for use in diagnosis or therapeutic applications.
Product Disclaimer:
Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application, despite our company's commitment to product quality and the rigorous internal QC inspections all products have undergone. Ultimate responsibility remains with the user for all operational processes, including storage, handling, and compliance with safety and biosafety protocols.
Target Profile
Gene Name:
LPIN2
Full Name:
Lipin 2
Gene Symbol:
MJDS; CRMO1
Gene ID:
9663
RefSeq ID-1:
NP_001362737.1
RefSeq ID-2:
NM_001375808.2
Summary:
LPIN2 belongs to the lipin family and is essential for normal triglyceride metabolism and the healthy development of adipose tissue. It is a major candidate gene for lipodystrophy in humans. Deficiencies in LPIN2 activity result in a failure to store fat properly in adipocytes, leading to secondary complications like fatty liver and insulin resistance.