AdipoUpX™ Human KIF7 MMLV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human KIF7 MMLV Particle (Overexpression) is a powerful gene delivery tool designed for the long-lasting overexpression of the human KIF7 gene. As a regulator of Hedgehog signaling and ciliary function, it is indispensable for researching syndromic obesity and developmental metabolic pathways. The MMLV system’s ability to integrate into the genome makes it ideal for establishing stable cell lines. Every batch is validated through comprehensive quality control (titer, sterility, and mycoplasma) to ensure product efficacy and reproducibility.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Complete verification of the vector genome's integrity was achieved for every viral preparation using the PCR method.

Sterility Test: The final viral preparation was confirmed sterile after testing.

Mycoplasma Test: Mycoplasma contamination testing met all release specifications for all product lots.

Other QC: We also provide additional testing services tailored to specific project requirements. Additionally, we conduct customized assessments to analyze the expression levels and biological functions of genetically modified organisms.

Storage: The product must be immediately transferred to -80 °C storage upon its arrival.

Stability: For long-term storage, the product guarantees excellent stability for 6-12 months at -80°C. After thawing, refrigeration at 4°C allows use of the working solution for 2-3 weeks.

Shipping Condition: Our MMLV retroviral products are shipped using dry ice.

Handling Notes: Due to their high sensitivity to temperature fluctuations and damaging freeze-thaw cycles, viral particles should be aliquoted into low-protein-binding tubes immediately upon receipt to maintain titer and product integrity. This procedure must be conducted within a biosafety cabinet.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: All products have undergone rigorous internal QC inspections as part of our company's commitment to product quality. However, due to the diversity and complexity of experimental conditions, users bear ultimate responsibility for product storage, handling, and compliance with all safety and biosafety protocols, and we offer no guarantee of product performance or experimental results in any specific application.

Target Profile

Gene Name: KIF7

Full Name: Kinesin family member 7

Gene Symbol: ACLS; AGBK; HLS2; MMEDF; JBTS12; UNQ340

Gene ID: 374654

RefSeq ID-1: NP_940927.2

RefSeq ID-2: NM_198525.3

Summary: KIF7 encodes a cilia-associated kinesin protein that regulates GLI transcription factors in the sonic hedgehog pathway. Through its influence on developmental signaling and ciliary function, KIF7 may affect hypothalamic pathways controlling appetite and energy balance, linking it to obesity phenotypes.

AdipoUpX™ Human KIF7 MMLV Particle (Overexpression)

Product Overview

Specification

Target Profile

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