AdipoUpX™ Human KCNJ5 Lentiviral Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human KCNJ5 Lentiviral Particle (Overexpression) is a high-titer system for the specific and stable expression of the human KCNJ5 gene. This potassium channel is an ideal tool for studying electrolyte balance and its emerging links to endocrine-regulated hypertension and metabolic health. All viral products undergo rigorous internal quality control to ensure reliability and safety. Our customizable platform offers high flexibility, allowing clients to freely select key functional components such as promoters and markers for precise cellular modeling.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: PCR analysis was performed to verify the complete genomic sequence of all viral vector preparations.

Sterility Test: This product was certified sterile following successful microbial growth analysis.

Mycoplasma Test: The production quality control confirmed the absence of any mycoplasmal agents.

Other QC: This comprehensive process includes customized supplementary testing alongside in vitro and in vivo transduction assessments to elucidate transgene expression and functionality.

Storage: To maintain product integrity, immediate transfer of the vector to a -80 °C is essential following its receipt.

Stability: Continuous storage at -80°C ensures excellent long-term stability for 6-12 months. Once thawed, the product's working solution should be refrigerated at 4°C and used within 2-3 weeks.

Shipping Condition: Our lentivirus viral products are shipped using dry ice.

Handling Notes: Ensure all operations are performed within a biosafety cabinet; upon receiving the vector, immediately aliquot it into low-protein-binding tubes and store according to specified conditions, thus avoiding the titer loss caused by sensitivity to temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application, despite our company's commitment to product quality and the rigorous internal QC inspections all products have undergone. Ultimate responsibility remains with the user for all operational processes, including storage, handling, and compliance with safety and biosafety protocols.

Target Profile

Gene Name: KCNJ5

Full Name: Potassium inwardly rectifying channel subfamily J member 5

Gene Symbol: CIR; GIRK4; KATP1; LQT13; KIR3.4

Gene ID: 3762

RefSeq ID-1: NP_000881.3

RefSeq ID-2: NM_000890.3

Summary: KCNJ5 encodes an inward-rectifier potassium channel subunit, controlling cellular membrane potential in endocrine tissues. Its activity can indirectly influence hormonal regulation of metabolism and fat accumulation, linking KCNJ5 to obesity-related endocrine dysfunction.

AdipoUpX™ Human KCNJ5 Lentiviral Particle (Overexpression)

Product Overview

Specification

Target Profile

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