AdipoUpX™ Human IL33 Lentiviral Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human IL33 Lentiviral Particle (Overexpression) is professionally engineered for the efficient and long-lasting overexpression of the human IL33 gene. This alarm is a key target for studying Type 2 innate immunity and its role in promoting adipose tissue browning and thermogenesis. Every batch is verified through comprehensive quality control screening (titer, sterility, and mycoplasma), ensuring that experimental results are repeatable and safe. The system features a modular design, allowing researchers to customize functional components to match their unique research models.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: PCR analysis was performed to verify the complete genomic sequence of all viral vector preparations.

Sterility Test: This product was certified sterile following successful microbial growth analysis.

Mycoplasma Test: The production quality control confirmed the absence of any mycoplasmal agents.

Other QC: This comprehensive process includes customized supplementary testing alongside in vitro and in vivo transduction assessments to elucidate transgene expression and functionality.

Storage: To maintain product integrity, immediate transfer of the vector to a -80 °C is essential following its receipt.

Stability: Continuous storage at -80°C ensures excellent long-term stability for 6-12 months. Once thawed, the product's working solution should be refrigerated at 4°C and used within 2-3 weeks.

Shipping Condition: Our lentivirus viral products are shipped using dry ice.

Handling Notes: Ensure all operations are performed within a biosafety cabinet; upon receiving the vector, immediately aliquot it into low-protein-binding tubes and store according to specified conditions, thus avoiding the titer loss caused by sensitivity to temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Given the diversity and complexity of experimental conditions, we do not guarantee product performance or experimental results in any specific application, despite our company's commitment to product quality and the rigorous internal QC inspections all products have undergone. Ultimate responsibility remains with the user for all operational processes, including storage, handling, and compliance with safety and biosafety protocols.

Target Profile

Gene Name: IL33

Full Name: Interleukin 33

Gene Symbol: DVS27; IL1F11; NF-HEV; NFEHEV; C9orf26

Gene ID: 90865

RefSeq ID-1: NP_001186569.1

RefSeq ID-2: NM_001199640.2

Summary: IL33 is a multi-functional cytokine that signals through the ST2 receptor to activate protective immune responses. In metabolic tissues, IL33 is vital for the maturation of Th2 cells and the maintenance of a "healthy" immune environment within fat. It helps balance the aggressive inflammation caused by overnutrition, playing a role in the preservation of insulin sensitivity.

AdipoUpX™ Human IL33 Lentiviral Particle (Overexpression)

Product Overview

Specification

Target Profile

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